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Gotu Kola Dosage Guide

Evidence:Moderate
·

This content is for informational purposes only and does not constitute medical advice. Statements about dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary — consult your healthcare provider before starting any supplement. Full disclaimer

General Dosage

500-1000mg standardized extract (6% triterpenes) daily

Maximum dose: 1000mg extract daily (higher doses increase liver toxicity risk)

Dosage Recommendations

General recommendation: 500-1000mg standardized extract (6% triterpenes) daily

Timing: Morning and evening; take with water on an empty stomach

Dosage by Condition

Anxiety
500mg extract twice dailyModerate
Cognitive enhancement
500-750mg dailyEmerging
Wound healing
60-120mg TECA daily (topical also effective)Moderate
Venous insufficiency
60-120mg TECA dailyModerate

Upper limit: 1000mg extract daily (higher doses increase liver toxicity risk)

Timing & Absorption

Morning and evening; take with water on an empty stomach

Can be taken with or without food.

Full Gotu Kola Guide

References

  1. RCTBradwejn J, Zhou Y, Koszycki D, Shlik J (2000). A double-blind, placebo-controlled study on the effects of Gotu Kola (Centella asiatica) on acoustic startle response in healthy subjects. Journal of Clinical Psychopharmacology. DOI PubMed
  2. RCTWattanathorn J, Mator L, Muchimapura S, et al. (2008). Positive modulation of cognition and mood in the healthy elderly volunteer following the administration of Centella asiatica. Journal of Ethnopharmacology. DOI PubMed
  3. ReviewBrinkhaus B, Lindner M, Schuppan D, Hahn EG (2000). Chemical, pharmacological and clinical profile of the East Asian medical plant Centella asiatica. Phytomedicine. DOI PubMed
  4. RCTWightman E, Khan J, Smith E, Rolfe V, et al. (2023). Chronic supplementation of a multi-ingredient herbal supplement increases speed of cognitive task performance alongside changes in the urinary metabolism of dopamine and the gut microbiome in cognitively intact older adults experiencing subjective memory decline: a randomized, placebo controlled, parallel groups investigation.. Frontiers in nutrition. DOI PubMed
  5. RCTPhoemsapthawee J, Ammawat W, Prasertsri P, Sathalalai P, et al. (2022). Does Gotu kola supplementation improve cognitive function, inflammation, and oxidative stress more than multicomponent exercise alone? - a randomized controlled study.. Journal of exercise rehabilitation. DOI PubMed
  6. RCTCarlson JJ, Farquhar JW, DiNucci E, Ausserer L, et al. (2007). Safety and efficacy of a ginkgo biloba-containing dietary supplement on cognitive function, quality of life, and platelet function in healthy, cognitively intact older adults.. Journal of the American Dietetic Association. DOI PubMed
  7. RCTKaziulin AN, Petukhov AB, Kucheriavyĭ IuA (2006). [Efficiency of includes of bioactive substances in diet of patient with hepatic encephalopathy].. Voprosy pitaniia. PubMed