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Types of Gotu Kola: Forms & Bioavailability

Evidence:Moderate
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This content is for informational purposes only and does not constitute medical advice. Statements about dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary — consult your healthcare provider before starting any supplement. Full disclaimer

Forms Comparison

FormBioavailabilityBest For
TECA (Titrated Extract)HighWound healing and venous insufficiency — the most clinically studied standardized form
ECa 233 ExtractHighCognitive and anxiety — standardized to triterpenoid glycosides
Dried Herb PowderModerateTraditional Ayurvedic use in capsules or teas

TECA (Titrated Extract)

Bioavailability: High. Best for: Wound healing and venous insufficiency — the most clinically studied standardized form.

ECa 233 Extract

Bioavailability: High. Best for: Cognitive and anxiety — standardized to triterpenoid glycosides.

Dried Herb Powder

Bioavailability: Moderate. Best for: Traditional Ayurvedic use in capsules or teas.

Full Gotu Kola Guide

References

  1. RCTBradwejn J, Zhou Y, Koszycki D, Shlik J (2000). A double-blind, placebo-controlled study on the effects of Gotu Kola (Centella asiatica) on acoustic startle response in healthy subjects. Journal of Clinical Psychopharmacology. DOI PubMed
  2. RCTWattanathorn J, Mator L, Muchimapura S, et al. (2008). Positive modulation of cognition and mood in the healthy elderly volunteer following the administration of Centella asiatica. Journal of Ethnopharmacology. DOI PubMed
  3. ReviewBrinkhaus B, Lindner M, Schuppan D, Hahn EG (2000). Chemical, pharmacological and clinical profile of the East Asian medical plant Centella asiatica. Phytomedicine. DOI PubMed
  4. RCTWightman E, Khan J, Smith E, Rolfe V, et al. (2023). Chronic supplementation of a multi-ingredient herbal supplement increases speed of cognitive task performance alongside changes in the urinary metabolism of dopamine and the gut microbiome in cognitively intact older adults experiencing subjective memory decline: a randomized, placebo controlled, parallel groups investigation.. Frontiers in nutrition. DOI PubMed
  5. RCTPhoemsapthawee J, Ammawat W, Prasertsri P, Sathalalai P, et al. (2022). Does Gotu kola supplementation improve cognitive function, inflammation, and oxidative stress more than multicomponent exercise alone? - a randomized controlled study.. Journal of exercise rehabilitation. DOI PubMed
  6. RCTCarlson JJ, Farquhar JW, DiNucci E, Ausserer L, et al. (2007). Safety and efficacy of a ginkgo biloba-containing dietary supplement on cognitive function, quality of life, and platelet function in healthy, cognitively intact older adults.. Journal of the American Dietetic Association. DOI PubMed
  7. RCTKaziulin AN, Petukhov AB, Kucheriavyĭ IuA (2006). [Efficiency of includes of bioactive substances in diet of patient with hepatic encephalopathy].. Voprosy pitaniia. PubMed