General Dosage
120-240 mg daily of oral hyaluronic acid
Maximum dose: Up to 240 mg/day used safely in clinical trials; no established upper limit for oral forms
Hyaluronic Acid Dosage Guide
This content is for informational purposes only and does not constitute medical advice. Consult your healthcare provider before starting any supplement. Full disclaimer
Dosage Recommendations
General recommendation: 120-240 mg daily of oral hyaluronic acid
Timing: Can be taken at any time of day with or without food
Dosage by Condition
| Condition | Recommended Dose | Evidence |
|---|---|---|
| Skin hydration | 120 mg daily | Strong |
| Wrinkle reduction | 120-240 mg daily for 12 weeks | Strong |
| Dry skin | 120 mg daily for 4-6 weeks | Moderate |
| Joint support | 200 mg daily | Moderate |
Upper limit: Up to 240 mg/day used safely in clinical trials; no established upper limit for oral forms
Timing & Absorption
Can be taken at any time of day with or without food
Can be taken with or without food.
References
- Oe M, Sakai S, Yoshida H, et al. (2017). Oral hyaluronan relieves wrinkles: a double-blinded, placebo-controlled study over a 12-week period. Clinical, Cosmetic and Investigational Dermatology. DOI PubMed
- Kawada C, Yoshida T, Yoshida H, et al. (2014). Ingested hyaluronan moisturizes dry skin. Nutrition Journal. DOI PubMed
- Hsu TF, Su ZR, Hsieh YH, et al. (2021). Oral hyaluronan relieves skin dryness and wrinkle: a systematic review. Journal of Cosmetic Dermatology. DOI PubMed
- Sato T, Sakamoto W, Odanaka W, et al. (2017). Clinical effects of dietary hyaluronic acid on dry, rough skin. Aesthetic Dermatology.