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Molybdenum Dosage Guide

Evidence:Moderate
·

This content is for informational purposes only and does not constitute medical advice. Statements about dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary — consult your healthcare provider before starting any supplement. Full disclaimer

General Dosage

45mcg daily (RDA); supplements typically provide 75-500mcg

Maximum dose: 2,000mcg/day (NIH UL); well-tolerated up to this level in healthy adults

Dosage Recommendations

General recommendation: 45mcg daily (RDA); supplements typically provide 75-500mcg

Timing: With or without food; well-absorbed regardless

Dosage by Condition

General health
45-150mcg dailyModerate
Sulfite sensitivity
100-500mcg dailyEmerging
Detoxification support
150-500mcg dailyPreliminary

Upper limit: 2,000mcg/day (NIH UL); well-tolerated up to this level in healthy adults

Timing & Absorption

With or without food; well-absorbed regardless

Can be taken with or without food.

Full Molybdenum Guide

References

  1. RCTTurnlund JR, Keyes WR, Peiffer GL (1995). Molybdenum absorption, excretion, and retention studied with stable isotopes in young men at five intakes of dietary molybdenum. American Journal of Clinical Nutrition. DOI PubMed
  2. ReviewSchwarz G, Mendel RR, Ribbe MW (2009). Molybdenum cofactors, enzymes and pathways. Nature. DOI PubMed
  3. Novotny JA, Peterson CA (2018). Molybdenum. Advances in Nutrition. DOI PubMed
  4. Meta-analysisDias RS, López S, Montanholi YR, Smith B, et al. (2013). A meta-analysis of the effects of dietary copper, molybdenum, and sulfur on plasma and liver copper, weight gain, and feed conversion in growing-finishing cattle.. Journal of animal science. DOI PubMed
  5. ReviewSchwahn BC, van Spronsen F, Misko A, Pavaine J, et al. (2024). Consensus guidelines for the diagnosis and management of isolated sulfite oxidase deficiency and molybdenum cofactor deficiencies.. Journal of inherited metabolic disease. DOI PubMed
  6. Niks D, Hille R (2019). Molybdenum- and tungsten-containing formate dehydrogenases and formylmethanofuran dehydrogenases: Structure, mechanism, and cofactor insertion.. Protein science : a publication of the Protein Society. DOI PubMed
  7. Fernández-Villa C, Rigueira L, López-Alonso M, Larrán B, et al. (2025). Identification of Patterns of Trace Mineral Deficiencies in Dairy and Beef Cattle Herds in Spain.. Animals : an open access journal from MDPI. DOI PubMed
Show 4 more references
  1. ReviewBerger MM, Shenkin A, Schweinlin A, Amrein K, et al. (2022). ESPEN micronutrient guideline.. Clinical nutrition (Edinburgh, Scotland). DOI PubMed
  2. Keskin H, Wang SM, Etemadi A, Fan JH, et al. (2021). Colorectal cancer in the Linxian China Nutrition Intervention Trial: Risk factors and intervention results.. PloS one. DOI PubMed
  3. Wang SM, Taylor PR, Fan JH, Pfeiffer RM, et al. (2018). Effects of Nutrition Intervention on Total and Cancer Mortality: 25-Year Post-trial Follow-up of the 5.25-Year Linxian Nutrition Intervention Trial.. Journal of the National Cancer Institute. DOI PubMed
  4. Kistner MJ, Wagner JJ, Evans J, Chalberg S, et al. (2017). The effects of molybdenum water concentration on feedlot performance, tissue mineral concentrations, and carcass quality of feedlot steers,. Journal of animal science. DOI PubMed