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Types of Rapamycin (Longevity Context): Forms & Bioavailability

Evidence:Emerging
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Forms Comparison

FormBioavailabilityBest For
Rapamycin / Sirolimus Tablets (prescription)Moderate (~15%)The only available form — oral tablets in 0.5mg, 1mg, and 2mg strengths; requires prescription and monitoring

Rapamycin / Sirolimus Tablets (prescription)

Bioavailability: Moderate (~15%). Best for: The only available form — oral tablets in 0.5mg, 1mg, and 2mg strengths; requires prescription and monitoring.

References

  1. RCTMannick JB, Del Giudice G, Sabatini M, et al. (2014). mTOR inhibition improves immune function in the elderly. Science Translational Medicine. DOI PubMed
  2. ReviewBlagosklonny MV (2019). Rapamycin for longevity: opinion article. Aging. DOI PubMed
  3. RCTHarrison DE, Strong R, Sharp ZD, et al. (2009). Rapamycin fed late in life extends lifespan in genetically heterogeneous mice. Nature. DOI PubMed