General Dosage
40-80mg total isoflavones daily from standardized red clover extract
Maximum dose: 160mg total isoflavones daily has been studied; standard range is 40-80mg
Red Clover Dosage Guide
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Dosage Recommendations
General recommendation: 40-80mg total isoflavones daily from standardized red clover extract
Timing: With meals, once or twice daily; consistent daily use for at least 12 weeks • Take with food for best absorption.
Dosage by Condition
Menopausal hot flashes
40-80mg isoflavones daily for 12+ weeksModerate
Bone mineral density support
40-80mg isoflavones dailyEmerging
Cardiovascular support
40-80mg isoflavones dailyPreliminary
| Condition | Recommended Dose | Evidence |
|---|---|---|
| Menopausal hot flashes | 40-80mg isoflavones daily for 12+ weeks | Moderate |
| Bone mineral density support | 40-80mg isoflavones daily | Emerging |
| Cardiovascular support | 40-80mg isoflavones daily | Preliminary |
Upper limit: 160mg total isoflavones daily has been studied; standard range is 40-80mg
Timing & Absorption
With meals, once or twice daily; consistent daily use for at least 12 weeks
Best taken with food for optimal absorption.
References
- Lethaby A, Marjoribanks J, Kronenberg F, et al. (2007). Phytoestrogens for menopausal vasomotor symptoms. Cochrane Database of Systematic Reviews. DOI PubMed
- Tice JA, Ettinger B, Ensrud K, et al. (2003). Phytoestrogen supplements for the treatment of hot flashes: the Isoflavone Clover Extract (ICE) Study. JAMA. DOI PubMed