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SupplementScience

Red Yeast Rice Dosage Guide

This content is for informational purposes only and does not constitute medical advice. Consult your healthcare provider before starting any supplement. Full disclaimer

General Dosage

1200-2400mg red yeast rice daily (standardized to ~10mg monacolin K)

Maximum dose: 4800mg/day (higher doses increase risk of statin-like side effects)

Dosage Recommendations

General recommendation: 1200-2400mg red yeast rice daily (standardized to ~10mg monacolin K)

Timing: Evening dosing preferred, as cholesterol synthesis peaks overnight • Take with food for best absorption.

Dosage by Condition

ConditionRecommended DoseEvidence
Elevated LDL cholesterol1200mg twice daily (providing 10mg monacolin K)Strong
Statin intolerance alternative1800mg twice dailyStrong
General cardiovascular maintenance1200mg dailyModerate

Upper limit: 4800mg/day (higher doses increase risk of statin-like side effects)

Timing & Absorption

Evening dosing preferred, as cholesterol synthesis peaks overnight

Best taken with food for optimal absorption.

References

  1. (). Effect of Xuezhikang, an extract from red yeast Chinese rice, on coronary events in a Chinese population with previous myocardial infarction. American Journal of Cardiology. DOI
  2. (). A meta-analysis of red yeast rice: an effective and relatively safe alternative approach for dyslipidemia. PLoS ONE. DOI
  3. (). Red yeast rice for dyslipidemia in statin-intolerant patients: a randomized trial. Annals of Internal Medicine. DOI