Skip to main content
SupplementScience

Saccharomyces Boulardii — Frequently Asked Questions

This content is for informational purposes only and does not constitute medical advice. Consult your healthcare provider before starting any supplement. Full disclaimer

Frequently Asked Questions

Can I take S. boulardii at the same time as antibiotics?

Yes — this is its primary advantage. S. boulardii is a yeast, so antibacterial antibiotics do not kill it. You can take it at the same time as your antibiotic without spacing doses apart. However, do not take it with antifungal medications like fluconazole, as these will kill the yeast.

How long should I take S. boulardii after finishing antibiotics?

Continue taking S. boulardii for at least 1-2 weeks after completing your antibiotic course. For C. difficile prevention, clinical trials used 4 weeks of supplementation. S. boulardii does not permanently colonize the gut — it washes out within 3-5 days of stopping.

Is S. boulardii safe for children?

Yes. S. boulardii has been extensively studied in pediatric populations and is recommended by the WHO as an adjunct for acute diarrhea in children. Standard pediatric dosing is 250mg twice daily. It is not recommended for premature infants or immunocompromised children.

Full Saccharomyces Boulardii Guide

References

  1. (). Systematic review with meta-analysis: Saccharomyces boulardii in the prevention of antibiotic-associated diarrhoea. Alimentary Pharmacology & Therapeutics. DOI
  2. (). Systematic review and meta-analysis of Saccharomyces boulardii in adult patients. World Journal of Gastroenterology. DOI