Skip to main content
SupplementScience

Saffron Extract Dosage Guide

This content is for informational purposes only and does not constitute medical advice. Consult your healthcare provider before starting any supplement. Full disclaimer

General Dosage

28-30mg standardized saffron extract daily (affron or equivalent)

Maximum dose: 100mg/day of standardized extract (doses up to 200mg studied short-term without toxicity, but no additional benefit)

Dosage Recommendations

General recommendation: 28-30mg standardized saffron extract daily (affron or equivalent)

Timing: Morning for mood support; evening for sleep benefits. Can be split into two 14-15mg doses.

Dosage by Condition

Mood support / mild depression
28-30mg standardized extract dailyStrong
Sleep quality
28mg affron daily, taken in the eveningModerate
PMS symptoms
30mg saffron extract daily through the luteal phaseModerate
Anxiety
30mg dailyEmerging

Upper limit: 100mg/day of standardized extract (doses up to 200mg studied short-term without toxicity, but no additional benefit)

Timing & Absorption

Morning for mood support; evening for sleep benefits. Can be split into two 14-15mg doses.

Can be taken with or without food.

Full Saffron Extract Guide

References

  1. (). Saffron (Crocus sativus L.) and major depressive disorder: a meta-analysis of randomized clinical trials. Journal of Integrative Medicine. DOI
  2. (). Comparison of Crocus sativus L. and imipramine in the treatment of mild to moderate depression: a pilot double-blind randomized trial. BMC Complementary and Alternative Medicine. DOI
  3. (). Saffron (Crocus sativus) for depression: a systematic review of clinical studies and examination of underlying antidepressant mechanisms of action. Human Psychopharmacology. DOI
  4. (). Crocus sativus L. (saffron) in the treatment of premenstrual syndrome: a double-blind, randomised and placebo-controlled trial. BJOG: An International Journal of Obstetrics and Gynaecology. DOI