General Dosage
20-30 mg saffron extract daily
Maximum dose: 200 mg/day short-term has been tolerated; standard supplemental doses are 20-30 mg/day
Saffron (Macular Health) Dosage Guide
Evidence:Emerging
·
This content is for informational purposes only and does not constitute medical advice. Statements about dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary — consult your healthcare provider before starting any supplement. Full disclaimer
Dosage Recommendations
General recommendation: 20-30 mg saffron extract daily
Timing: Can be taken at any time of day; with or without food
Dosage by Condition
Early AMD support
20 mg dailyEmerging
Macular function
20-30 mg dailyEmerging
Retinal neuroprotection
20 mg dailyPreliminary
| Condition | Recommended Dose | Evidence |
|---|---|---|
| Early AMD support | 20 mg daily | Emerging |
| Macular function | 20-30 mg daily | Emerging |
| Retinal neuroprotection | 20 mg daily | Preliminary |
Upper limit: 200 mg/day short-term has been tolerated; standard supplemental doses are 20-30 mg/day
Timing & Absorption
Can be taken at any time of day; with or without food
Can be taken with or without food.
References
- RCTFalsini B, Piccardi M, Minnella A, et al. (2010). Influence of saffron supplementation on retinal flicker sensitivity in early age-related macular degeneration. Investigative Ophthalmology & Visual Science. DOI PubMed
- ObservationalPiccardi M, Marangoni D, Minnella AM, et al. (2012). A longitudinal follow-up study of saffron supplementation in early age-related macular degeneration. Evidence-Based Complementary and Alternative Medicine. DOI PubMed
- RCTMarangoni D, Falsini B, Piccardi M, et al. (2013). Functional effect of saffron supplementation and risk genotypes in early age-related macular degeneration. Nutrients. DOI PubMed