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Saffron (Macular Health) Research & Evidence

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Evidence Level

Emerging

Saffron is one of the most exciting emerging therapies for AMD. Falsini et al. (2010) demonstrated that 20 mg/day improved focal ERG amplitude and visual acuity in early AMD patients within 3 months. A follow-up 15-month study confirmed sustained benefits. Marangoni et al. (2013) showed saffron also improved macular function in Stargardt macular dystrophy. While study sizes remain small, the consistency of positive results across multiple trials is noteworthy.

Evidence by Condition

ConditionStudied DoseEvidence
Early AMD support20 mg dailyEmerging
Macular function20-30 mg dailyEmerging
Retinal neuroprotection20 mg dailyPreliminary
Full Saffron (Macular Health) Guide

References

  1. (). Influence of saffron supplementation on retinal flicker sensitivity in early age-related macular degeneration. Investigative Ophthalmology & Visual Science. DOI
  2. (). A longitudinal follow-up study of saffron supplementation in early age-related macular degeneration. Evidence-Based Complementary and Alternative Medicine. DOI
  3. (). Functional effect of saffron supplementation and risk genotypes in early age-related macular degeneration. Nutrients. DOI