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Vitamin B2 (Riboflavin) Dosage Guide

Evidence:Strong
·

This content is for informational purposes only and does not constitute medical advice. Statements about dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary — consult your healthcare provider before starting any supplement. Full disclaimer

General Dosage

1.1 mg (women) to 1.3 mg (men) daily as RDA; 400 mg daily for migraine prevention

Maximum dose: No established upper limit — low toxicity due to limited absorption at high doses; excess excreted in urine (causing bright yellow color)

Dosage Recommendations

General recommendation: 1.1 mg (women) to 1.3 mg (men) daily as RDA; 400 mg daily for migraine prevention

Timing: With meals; split doses for amounts above 50 mg to improve absorption • Take with food for best absorption.

Dosage by Condition

General health
1.1-1.3 mg dailyStrong
Migraine prevention
400 mg daily for at least 3 monthsStrong
Antioxidant support
10-25 mg dailyModerate

Upper limit: No established upper limit — low toxicity due to limited absorption at high doses; excess excreted in urine (causing bright yellow color)

Timing & Absorption

With meals; split doses for amounts above 50 mg to improve absorption

Best taken with food for optimal absorption.

Full Vitamin B2 (Riboflavin) Guide

References

  1. RCTSchoenen J, Jacquy J, Lenaerts M (1998). Effectiveness of high-dose riboflavin in migraine prophylaxis: a randomized controlled trial. Neurology. DOI PubMed
  2. ReviewThompson DF, Saluja HS (2017). Prophylaxis of migraine headaches with riboflavin: a systematic review. Journal of Clinical Pharmacy and Therapeutics. DOI PubMed
  3. ReviewPowers HJ (2003). Riboflavin (vitamin B-2) and health. American Journal of Clinical Nutrition. DOI PubMed
  4. RCTKałużna-Czaplińska J, Socha E, Rynkowski J (2011). B vitamin supplementation reduces excretion of urinary dicarboxylic acids in autistic children.. Nutrition research (New York, N.Y.). DOI PubMed