Skip to main content
SupplementScience

Vitamin B6 (Pyridoxine) Dosage Guide

This content is for informational purposes only and does not constitute medical advice. Consult your healthcare provider before starting any supplement. Full disclaimer

General Dosage

1.3 mg daily (adults 19-50); 1.5 mg (women 51+); 1.7 mg (men 51+)

Maximum dose: 100 mg/day (NIH UL); chronic doses above 200 mg/day risk peripheral neuropathy

Dosage Recommendations

General recommendation: 1.3 mg daily (adults 19-50); 1.5 mg (women 51+); 1.7 mg (men 51+)

Timing: With food to reduce nausea; morning for energy support • Take with food for best absorption.

Dosage by Condition

General health
1.3-2.0 mg dailyStrong
Morning sickness
10-25 mg three times dailyStrong
PMS relief
50-100 mg dailyModerate
Homocysteine reduction
25-50 mg daily with B12 and folateStrong

Upper limit: 100 mg/day (NIH UL); chronic doses above 200 mg/day risk peripheral neuropathy

Timing & Absorption

With food to reduce nausea; morning for energy support

Best taken with food for optimal absorption.

References

  1. (). Efficacy of vitamin B-6 in the treatment of premenstrual syndrome: systematic review. BMJ. DOI
  2. (). Nausea and Vomiting of Pregnancy. Obstetrics & Gynecology. DOI
  3. (). Vitamin B6 level is associated with symptoms of depression. Psychotherapy and Psychosomatics. DOI