General Dosage
20-40mg standardized fruit extract daily (equivalent to Ze 440 or BNO 1095 extracts)
Maximum dose: 40mg standardized extract daily; higher doses have not shown additional benefit and may cause side effects
Vitex (Chasteberry) Dosage Guide
This content is for informational purposes only and does not constitute medical advice. Consult your healthcare provider before starting any supplement. Full disclaimer
Dosage Recommendations
General recommendation: 20-40mg standardized fruit extract daily (equivalent to Ze 440 or BNO 1095 extracts)
Timing: Morning on an empty stomach; consistent daily dosing is more important than timing
Dosage by Condition
| Condition | Recommended Dose | Evidence |
|---|---|---|
| PMS symptom relief | 20mg standardized extract daily for 3+ cycles | Strong |
| Menstrual cycle regulation | 20-40mg standardized extract daily | Moderate |
| Mild hyperprolactinemia | 20-40mg daily under medical supervision | Moderate |
| Luteal phase support | 20-40mg daily for 3-6 months | Emerging |
Upper limit: 40mg standardized extract daily; higher doses have not shown additional benefit and may cause side effects
Timing & Absorption
Morning on an empty stomach; consistent daily dosing is more important than timing
Can be taken with or without food.
References
- Schellenberg R (2001). Treatment for the premenstrual syndrome with agnus castus fruit extract: prospective, randomised, placebo controlled study. BMJ. DOI PubMed
- Verkaik S, Moll AC, Steegers-Theunissen RP, et al. (2017). The treatment of premenstrual syndrome with preparations of Vitex agnus castus: a systematic review and meta-analysis. American Journal of Obstetrics and Gynecology. DOI PubMed
- Wuttke W, Jarry H, Christoffel V, Spengler B, Seidlová-Wuttke D (2003). Chaste tree (Vitex agnus-castus) — pharmacology and clinical indications. Phytomedicine. DOI PubMed