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Types of Vitex (Chasteberry): Forms & Bioavailability

Evidence:Strong
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Forms Comparison

FormBioavailabilityBest For
Standardized Fruit Extract (Ze 440 or BNO 1095)HighPMS and cycle regulation — these are the clinically studied branded extracts with consistent results in trials
Dried Fruit PowderModerateTraditional use — less standardized but widely available; higher doses (500-1000mg) may be needed to match extract efficacy
Liquid Tincture (1:5)Moderate-HighFlexible dosing — allows easy dose adjustment; typical dose is 40 drops (approx 2ml) daily

Standardized Fruit Extract (Ze 440 or BNO 1095)

Bioavailability: High. Best for: PMS and cycle regulation — these are the clinically studied branded extracts with consistent results in trials.

Dried Fruit Powder

Bioavailability: Moderate. Best for: Traditional use — less standardized but widely available; higher doses (500-1000mg) may be needed to match extract efficacy.

Liquid Tincture (1:5)

Bioavailability: Moderate-High. Best for: Flexible dosing — allows easy dose adjustment; typical dose is 40 drops (approx 2ml) daily.

References

  1. RCTSchellenberg R (2001). Treatment for the premenstrual syndrome with agnus castus fruit extract: prospective, randomised, placebo controlled study. BMJ. DOI PubMed
  2. Meta-analysisVerkaik S, Moll AC, Steegers-Theunissen RP, et al. (2017). The treatment of premenstrual syndrome with preparations of Vitex agnus castus: a systematic review and meta-analysis. American Journal of Obstetrics and Gynecology. DOI PubMed
  3. RCTWuttke W, Jarry H, Christoffel V, Spengler B, Seidlová-Wuttke D (2003). Chaste tree (Vitex agnus-castus) — pharmacology and clinical indications. Phytomedicine. DOI PubMed