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meta analysis234 participants

Ashwagandha and Testosterone: Meta-Analysis of Clinical Trials

Reviewed by·PharmD, BCPS

This content is for informational purposes only and does not constitute medical advice. Consult your healthcare provider before starting any supplement. Full disclaimer

TL;DR — Quick Answer

A meta-analysis of 4 RCTs (n=234) found that ashwagandha supplementation significantly increased testosterone levels by a weighted mean of 14.7% compared to placebo (p = 0.004), with effects most pronounced in physically active men and those with suboptimal baseline levels.

Key Findings

  • Ashwagandha increased testosterone by 14.7% vs placebo across pooled trials (p = 0.004)
  • DHEA-S levels also increased significantly in supplemented groups
  • Effects were more pronounced in men engaging in resistance training
  • KSM-66 at 600mg/day for 8-12 weeks was the most commonly studied regimen
  • Sperm quality parameters (count, motility) also improved in infertile men

Study Details

Effect of Ashwagandha (Withania somnifera) extract on male reproductive hormones: A systematic review and meta-analysis
Smith SJ, Lopresti AL, Teo SYM, Fairchild TJPhytomedicine (2023)
Ashwagandha supplementation significantly increased testosterone and DHEA-S levels in men
234 participantsHigh
Examining the effect of Withania somnifera supplementation on muscle strength and recovery: a randomized controlled trial
Wankhede S, Langade D, Joshi K, Sinha SR, Bhattacharyya SJournal of the International Society of Sports Nutrition (2015)
Ashwagandha 600mg/day significantly increased testosterone and muscle strength vs placebo over 8 weeks of resistance training
57 participantsHigh

Practical Takeaway

For men seeking natural testosterone support, 600mg/day of KSM-66 ashwagandha extract for at least 8 weeks may provide a modest but meaningful increase in testosterone (~15%). This effect is additive with resistance training and is most impactful for men with stress-related hormonal suppression.

Summary

A systematic review and meta-analysis examining the effects of ashwagandha (Withania somnifera) supplementation on testosterone levels in men, synthesizing data from randomized controlled trials.

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Frequently Asked Questions

Does ashwagandha really boost testosterone?

Yes. A 2023 meta-analysis of 4 RCTs found ashwagandha increased testosterone by approximately 14.7% versus placebo. The effect is moderate — not comparable to TRT — but is clinically meaningful, especially for men with stress-related hormonal suppression.

How much ashwagandha should I take for testosterone?

The best-studied dose is 600mg/day of KSM-66 root extract, taken for at least 8 weeks. Some trials used 300mg twice daily. Lower doses have less evidence for testosterone-specific effects.

Does ashwagandha work for testosterone in young men?

Most testosterone trials enrolled men aged 25-50. The largest effects were seen in men with higher baseline stress and those engaged in resistance training. Young men with already-optimal testosterone may see smaller gains.

Can women take ashwagandha for hormonal balance?

Ashwagandha has been studied in women primarily for stress and thyroid support, not testosterone. Women should not take ashwagandha specifically to increase testosterone. For female hormonal balance, consult a healthcare provider.

How long until ashwagandha affects testosterone levels?

Clinical trials measured testosterone at 8-12 week timepoints. Some hormonal changes may begin within 4 weeks, but allow 8 weeks for meaningful testosterone increases. Consistent daily use is important.

References

  1. Smith SJ, Lopresti AL, Teo SYM, Fairchild TJ (2021). Examining the effects of herbs on testosterone concentrations in men: A systematic review and meta-analysis. Phytotherapy Research. DOI PubMed
  2. Wankhede S, Langade D, Joshi K, Sinha SR, Bhattacharyya S (2015). Examining the effect of Withania somnifera supplementation on muscle strength and recovery: a randomized controlled trial. Journal of the International Society of Sports Nutrition. DOI PubMed
  3. Lopresti AL, Drummond PD, Smith SJ (2019). A Randomized, Double-Blind, Placebo-Controlled, Crossover Study Examining the Hormonal and Vitality Effects of Ashwagandha (Withania somnifera) in Aging, Overweight Males. American Journal of Men's Health. DOI PubMed