General Dosage
1,500 mg daily divided into 3 doses of 500 mg with meals
Maximum dose: 1,500 mg/day of berberine HCl; GI side effects increase at higher doses
Berberine (Weight Management) Dosage Guide
This content is for informational purposes only and does not constitute medical advice. Consult your healthcare provider before starting any supplement. Full disclaimer
Dosage Recommendations
General recommendation: 1,500 mg daily divided into 3 doses of 500 mg with meals
Timing: Take 500 mg with each main meal; spreading doses improves absorption and tolerability • Take with food for best absorption.
Dosage by Condition
Metabolic weight management
1,500 mg daily (3 × 500 mg)Strong
Blood sugar control
900-1,500 mg dailyStrong
Dihydroberberine
150-300 mg dailyEmerging
| Condition | Recommended Dose | Evidence |
|---|---|---|
| Metabolic weight management | 1,500 mg daily (3 × 500 mg) | Strong |
| Blood sugar control | 900-1,500 mg daily | Strong |
| Dihydroberberine | 150-300 mg daily | Emerging |
Upper limit: 1,500 mg/day of berberine HCl; GI side effects increase at higher doses
Timing & Absorption
Take 500 mg with each main meal; spreading doses improves absorption and tolerability
Best taken with food for optimal absorption.