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| Form | Bioavailability | Best For |
|---|---|---|
| Berberine HCl | Low (5%) | Standard form — most clinical trials use berberine HCl; low absorption mitigated by frequent dosing |
| Dihydroberberine | High (5x berberine HCl) | Enhanced absorption form — lower doses needed; may reduce GI side effects |
| Berberine Phytosome | High | Phospholipid-complexed form for improved bioavailability |
Bioavailability: Low (5%). Best for: Standard form — most clinical trials use berberine HCl; low absorption mitigated by frequent dosing.
Bioavailability: High (5x berberine HCl). Best for: Enhanced absorption form — lower doses needed; may reduce GI side effects.
Bioavailability: High. Best for: Phospholipid-complexed form for improved bioavailability.