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Bitter Orange (Synephrine) Dosage Guide

This content is for informational purposes only and does not constitute medical advice. Consult your healthcare provider before starting any supplement. Full disclaimer

General Dosage

25-50 mg synephrine daily, alone or before exercise

Maximum dose: 50 mg synephrine/day for most adults; avoid combining with high-dose caffeine or other stimulants

Dosage Recommendations

General recommendation: 25-50 mg synephrine daily, alone or before exercise

Timing: Take in the morning or before exercise; avoid evening dosing

Dosage by Condition

Thermogenesis
25-50 mg synephrine dailyEmerging
Pre-exercise fat oxidation
2-3 mg/kg synephrine 60 min before exerciseEmerging

Upper limit: 50 mg synephrine/day for most adults; avoid combining with high-dose caffeine or other stimulants

Timing & Absorption

Take in the morning or before exercise; avoid evening dosing

Can be taken with or without food.

Full Bitter Orange (Synephrine) Guide

References

  1. (). A review of the human clinical studies involving Citrus aurantium (bitter orange) extract and its primary protoalkaloid p-synephrine. International Journal of Medical Sciences. DOI