General Dosage
500-1000mg processed (zhi) root extract daily
Maximum dose: 1000mg processed extract daily (err on lower side due to liver concerns)
He Shou Wu Dosage Guide
This content is for informational purposes only and does not constitute medical advice. Consult your healthcare provider before starting any supplement. Full disclaimer
Dosage Recommendations
General recommendation: 500-1000mg processed (zhi) root extract daily
Timing: With meals; limit use to 3-month cycles with liver function monitoring • Take with food for best absorption.
Dosage by Condition
| Condition | Recommended Dose | Evidence |
|---|---|---|
| General tonic/longevity | 500-1000mg processed extract daily | Preliminary |
| Cholesterol support | 500-1000mg daily | Preliminary |
| Hair health | 500mg daily (traditional) | Insufficient |
Upper limit: 1000mg processed extract daily (err on lower side due to liver concerns)
Timing & Absorption
With meals; limit use to 3-month cycles with liver function monitoring
Best taken with food for optimal absorption.
References
- Lei X, Chen J, Ren J, et al. (2015). Liver damage associated with Polygonum multiflorum Thunb.: a systematic review of case reports and case series. Evidence-Based Complementary and Alternative Medicine. DOI PubMed
- Sun YN, Cui L, Li W, et al. (2016). Promotion of neuroprotective effects of Polygonum multiflorum: a review of pharmacological activities and mechanisms. Chinese Journal of Integrative Medicine. DOI PubMed