General Dosage
500-1000mg processed (zhi) root extract daily
Maximum dose: 1000mg processed extract daily (err on lower side due to liver concerns)
He Shou Wu Dosage Guide
Evidence:Preliminary
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Dosage Recommendations
General recommendation: 500-1000mg processed (zhi) root extract daily
Timing: With meals; limit use to 3-month cycles with liver function monitoring • Take with food for best absorption.
Dosage by Condition
General tonic/longevity
500-1000mg processed extract dailyPreliminary
Cholesterol support
500-1000mg dailyPreliminary
Hair health
500mg daily (traditional)Insufficient
| Condition | Recommended Dose | Evidence |
|---|---|---|
| General tonic/longevity | 500-1000mg processed extract daily | Preliminary |
| Cholesterol support | 500-1000mg daily | Preliminary |
| Hair health | 500mg daily (traditional) | Insufficient |
Upper limit: 1000mg processed extract daily (err on lower side due to liver concerns)
Timing & Absorption
With meals; limit use to 3-month cycles with liver function monitoring
Best taken with food for optimal absorption.
References
- ReviewLei X, Chen J, Ren J, et al. (2015). Liver damage associated with Polygonum multiflorum Thunb.: a systematic review of case reports and case series. Evidence-Based Complementary and Alternative Medicine. DOI PubMed
- ReviewSun YN, Cui L, Li W, et al. (2016). Promotion of neuroprotective effects of Polygonum multiflorum: a review of pharmacological activities and mechanisms. Chinese Journal of Integrative Medicine. DOI