Skip to main content
Supplement ScienceSupplementScience

Types of He Shou Wu: Forms & Bioavailability

Evidence:Preliminary
·

This content is for informational purposes only and does not constitute medical advice. Statements about dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary — consult your healthcare provider before starting any supplement. Full disclaimer

Forms Comparison

FormBioavailabilityBest For
Processed (Zhi) Root ExtractModerateOnly recommended form — processing reduces anthraquinones (hepatotoxic compounds)
Processed Root PowderLow-ModerateTraditional TCM decoctions — always use processed, never raw

Processed (Zhi) Root Extract

Bioavailability: Moderate. Best for: Only recommended form — processing reduces anthraquinones (hepatotoxic compounds).

Processed Root Powder

Bioavailability: Low-Moderate. Best for: Traditional TCM decoctions — always use processed, never raw.

References

  1. ReviewLei X, Chen J, Ren J, et al. (2015). Liver damage associated with Polygonum multiflorum Thunb.: a systematic review of case reports and case series. Evidence-Based Complementary and Alternative Medicine. DOI PubMed
  2. ReviewSun YN, Cui L, Li W, et al. (2016). Promotion of neuroprotective effects of Polygonum multiflorum: a review of pharmacological activities and mechanisms. Chinese Journal of Integrative Medicine. DOI