General Dosage
600-1,200 mg daily in divided doses
Maximum dose: 2,400 mg/day is commonly used in psychiatric trials; higher doses used under medical supervision
NAC (N-Acetyl Cysteine) Dosage Guide
This content is for informational purposes only and does not constitute medical advice. Consult your healthcare provider before starting any supplement. Full disclaimer
Dosage Recommendations
General recommendation: 600-1,200 mg daily in divided doses
Timing: Take on an empty stomach for better absorption; can be divided into 2-3 doses
Dosage by Condition
| Condition | Recommended Dose | Evidence |
|---|---|---|
| Glutathione support | 600-1,200 mg daily | Strong |
| Respiratory mucus thinning | 600-1,200 mg daily | Strong |
| Psychiatric applications | 1,200-2,400 mg daily | Moderate |
| Liver support | 600-1,200 mg daily | Moderate |
Upper limit: 2,400 mg/day is commonly used in psychiatric trials; higher doses used under medical supervision
Timing & Absorption
Take on an empty stomach for better absorption; can be divided into 2-3 doses
Can be taken with or without food.
References
- Grant JE, Odlaug BL, Kim SW (2009). N-acetylcysteine, a glutamate modulator, in the treatment of trichotillomania: a double-blind, placebo-controlled study. Archives of General Psychiatry. DOI PubMed
- Rushworth GF, Megson IL (2014). Existing and potential therapeutic uses for N-acetylcysteine: the need for conversion to intracellular glutathione for antioxidant benefits. Pharmacology & Therapeutics. DOI PubMed