General Dosage
2-4g combined EPA + DHA daily, taken with meals containing fat
Maximum dose: Up to 5g/day EPA+DHA is considered safe by EFSA; FDA has approved 4g/day prescription formulations
Omega-3 Fish Oil Dosage Guide
This content is for informational purposes only and does not constitute medical advice. Consult your healthcare provider before starting any supplement. Full disclaimer
Dosage Recommendations
General recommendation: 2-4g combined EPA + DHA daily, taken with meals containing fat
Timing: Take with meals containing fat to maximize absorption; split into 2 daily doses if using >2g • Take with food for best absorption.
Dosage by Condition
| Condition | Recommended Dose | Evidence |
|---|---|---|
| General anti-inflammatory | 2-3g EPA+DHA daily | Strong |
| Hypertriglyceridemia | 3-4g EPA+DHA daily | Strong |
| Rheumatoid arthritis | 3-6g EPA+DHA daily | Moderate |
Upper limit: Up to 5g/day EPA+DHA is considered safe by EFSA; FDA has approved 4g/day prescription formulations
Timing & Absorption
Take with meals containing fat to maximize absorption; split into 2 daily doses if using >2g
Best taken with food for optimal absorption.
References
- Li N, Jia X, Chen CYO, et al. (2019). Almond consumption and cardiovascular risk factors: a systematic review and meta-analysis of randomized controlled trials. Advances in Nutrition. DOI PubMed
- Bhatt DL, Steg PG, Miller M, et al. (2019). Cardiovascular risk reduction with icosapent ethyl for hypertriglyceridemia. New England Journal of Medicine. DOI PubMed
- Calder PC (2017). Omega-3 fatty acids and inflammatory processes: from molecules to man. Biochemical Society Transactions. DOI PubMed