Types of PQQ: Forms & Bioavailability

SupplementScience.ai Editorial Team·Evidence-Based Supplement Research

Published Mar 11, 2026

This content is for informational purposes only and does not constitute medical advice. Consult your healthcare provider before starting any supplement. Full disclaimer

Forms Comparison

Form	Bioavailability	Best For
BioPQQ Capsules	High	Clinically validated — branded form produced by Mitsubishi, used in most clinical trials
PQQ Disodium Salt Capsules	High	Standard supplemental form — the most common PQQ salt used in supplements
PQQ + CoQ10 Combination	High	Synergistic mitochondrial support — PQQ creates new mitochondria while CoQ10 fuels them

BioPQQ Capsules

Bioavailability: High. Best for: Clinically validated — branded form produced by Mitsubishi, used in most clinical trials.

PQQ Disodium Salt Capsules

Bioavailability: High. Best for: Standard supplemental form — the most common PQQ salt used in supplements.

PQQ + CoQ10 Combination

Bioavailability: High. Best for: Synergistic mitochondrial support — PQQ creates new mitochondria while CoQ10 fuels them.

Full PQQ Guide

References

Harris CB, Chowanadisai W, Mishchuk DO, et al. (2013). Dietary pyrroloquinoline quinone (PQQ) alters indicators of inflammation and mitochondrial-related metabolism in human subjects. Journal of Nutritional Biochemistry. DOI PubMed
Nakano M, Ubukata K, Yamamoto T, Yamaguchi H (2009). Effect of pyrroloquinoline quinone (PQQ) on mental status of middle-aged and elderly persons. Food Style 21.
Chowanadisai W, Bauerly KA, Tchaparian E, et al. (2010). Pyrroloquinoline quinone stimulates mitochondrial biogenesis through cAMP response element-binding protein phosphorylation and increased PGC-1alpha expression. Journal of Biological Chemistry. DOI PubMed