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Resveratrol Dosage Guide

Evidence:Moderate
·

This content is for informational purposes only and does not constitute medical advice. Statements about dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary — consult your healthcare provider before starting any supplement. Full disclaimer

General Dosage

150-500mg trans-resveratrol daily with a fat-containing meal

Maximum dose: 1500mg/day (GI side effects increase above 1000mg)

Dosage Recommendations

General recommendation: 150-500mg trans-resveratrol daily with a fat-containing meal

Timing: With a meal containing fat to improve absorption; morning or evening • Take with food for best absorption.

Dosage by Condition

General longevity / sirtuin activation
150-500mg dailyEmerging
Glucose metabolism
150-250mg dailyModerate
Cardiovascular support
250-500mg dailyEmerging

Upper limit: 1500mg/day (GI side effects increase above 1000mg)

Timing & Absorption

With a meal containing fat to improve absorption; morning or evening

Best taken with food for optimal absorption.

Full Resveratrol Guide

References

  1. RCTTimmers S, Konings E, de Vogel-van den Bosch J, et al. (2011). Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans. Cell Metabolism. DOI PubMed
  2. Meta-analysisRodrigues Uggioni ML, Ronsani L, Motta S, Denoni Júnior JC, et al. (2025). Effects of resveratrol on the lipid profile of post-menopause women: Systematic review and meta-analysis.. Nutrition, metabolism, and cardiovascular diseases : NMCD. DOI PubMed
  3. Meta-analysisLahouti M, Arzhang P, Azadbakht L (2025). A Systematic Review and Meta-Analysis of Randomized Controlled Trials on the Impact of Resveratrol Supplementation on Anthropometric Indices in Patients With Type 2 Diabetes.. Phytotherapy research : PTR. DOI PubMed
  4. Meta-analysisDamay VA, Ivan I (2024). Resveratrol as an Anti-inflammatory Agent in Coronary Artery Disease: A Systematic Review, Meta-Analysis and Meta-Regression.. Chinese journal of integrative medicine. DOI PubMed
  5. Meta-analysisLarik MO, Ahmed A, Khan L, Iftekhar MA (2024). Effects of resveratrol on polycystic ovarian syndrome: a systematic review and meta-analysis of randomized controlled trials.. Endocrine. DOI PubMed
  6. Meta-analysisAlam MK, Alqhtani NR, Alnufaiy B, Alqahtani AS, et al. (2024). A systematic review and meta-analysis of the impact of resveratrol on oral cancer: potential therapeutic implications.. BMC oral health. DOI PubMed
  7. Meta-analysisMolani-Gol R, Rafraf M (2024). Effects of resveratrol on the anthropometric indices and inflammatory markers: an umbrella meta-analysis.. European journal of nutrition. DOI PubMed
Show 3 more references
  1. Meta-analysisLiu X, Gu X, Zhang J, Li X, et al. (2024). Resveratrol delays the progression of diabetic nephropathy through multiple pathways: A dose-response meta-analysis based on animal models.. Journal of diabetes. DOI PubMed
  2. Meta-analysisAli Fadlalmola H, Elhusein AM, Al-Sayaghi KM, Albadrani MS, et al. (2023). Efficacy of resveratrol in women with polycystic ovary syndrome: a systematic review and meta-analysis of randomized clinical trials.. The Pan African medical journal. DOI PubMed
  3. Meta-analysisLuís Â, Marcelino H, Domingues F, Pereira L, et al. (2023). Therapeutic Potential of Resveratrol for Glioma: A Systematic Review and Meta-Analysis of Animal Model Studies.. International journal of molecular sciences. DOI PubMed