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Resveratrol — Frequently Asked Questions

This content is for informational purposes only and does not constitute medical advice. Consult your healthcare provider before starting any supplement. Full disclaimer

Frequently Asked Questions

Can I get enough resveratrol from red wine?

No. Red wine contains only 1-7mg resveratrol per liter. To get a clinical dose of 150-500mg, you would need to drink 20-500 glasses daily — obviously impractical and unhealthy. Supplementation is the only way to achieve therapeutic levels.

What is the difference between trans- and cis-resveratrol?

Trans-resveratrol is the biologically active form studied in clinical trials. Cis-resveratrol is less stable and less studied. Quality supplements use trans-resveratrol, often from Japanese knotweed (Polygonum cuspidatum), which is the richest supplemental source.

Does resveratrol actually extend lifespan?

Resveratrol extends lifespan in yeast, worms, and some fish studies, but no human longevity data exists. It does activate SIRT1 (a longevity-associated enzyme) and improve metabolic markers in humans. Whether this translates to lifespan extension remains unproven.

Full Resveratrol Guide

References

  1. (). Effect of resveratrol supplementation on inflammatory markers: a systematic review and meta-analysis of randomized controlled trials. Clinical Therapeutics. DOI
  2. (). Resveratrol supplementation significantly influences obesity measures: a systematic review and dose-response meta-analysis of randomized controlled trials. Obesity Reviews. DOI
  3. (). The therapeutic potential of resveratrol: a review of clinical trials. NPJ Precision Oncology. DOI