SupplementScience

Benefits of Ashwagandha

DJP
Reviewed by , MD, Board Certified Internal Medicine

This content is for informational purposes only and does not constitute medical advice. Consult your healthcare provider before starting any supplement. Full disclaimer

Evidence-Based Benefits

  • Stress and cortisol reduction — a 2019 meta-analysis of 5 RCTs found ashwagandha reduced serum cortisol by 23% compared to placebo
  • Anxiety relief — KSM-66 extract at 300mg twice daily reduced anxiety scores by 44% on the HAM-A scale
  • Sleep improvement — 300mg twice daily improved sleep quality scores and reduced sleep onset latency
  • Testosterone support — 600mg daily increased testosterone by 14.7% in a 2019 RCT of 57 men
  • Exercise performance — improved VO2 max and strength in resistance-trained individuals

What the Research Says

Ashwagandha has one of the strongest evidence bases among adaptogens. A comprehensive 2019 meta-analysis published in the Journal of Alternative and Complementary Medicine, analyzing 5 randomized controlled trials, found statistically significant reductions in stress and anxiety scores. The most studied extract, KSM-66, has over 22 published clinical trials demonstrating benefits for stress, sleep, cognitive function, and sexual health.

Related Conditions

References

  1. (). An Alternative Treatment for Anxiety: A Systematic Review of Human Trial Results Reported for the Ayurvedic Herb Ashwagandha. Journal of Alternative and Complementary Medicine. DOI
  2. (). An investigation into the stress-relieving and pharmacological actions of an ashwagandha extract. Medicine. DOI