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SupplementScience

Benefits of Calcium

This content is for informational purposes only and does not constitute medical advice. Consult your healthcare provider before starting any supplement. Full disclaimer

Evidence-Based Benefits

  • Bone density preservation — the WHI trial (n=36,282) found calcium + vitamin D supplementation reduced hip fracture risk by 29% in adherent women over 60
  • Fracture prevention — a 2015 meta-analysis in BMJ (Bolland et al.) of 59 RCTs found calcium supplements modestly increase bone mineral density at all sites
  • Muscle function — calcium ions trigger actin-myosin cross-bridge cycling, making it essential for every muscle contraction
  • Colon health — a meta-analysis of 10 studies found calcium supplementation associated with a 22% reduced risk of colorectal adenomas
  • Blood pressure — modest reductions in systolic blood pressure (1-2 mmHg) observed in meta-analyses of calcium supplementation trials

What the Research Says

Calcium supplementation has a large evidence base, primarily for bone health. The Women's Health Initiative (Jackson et al., 2006, n=36,282) demonstrated that calcium + vitamin D reduced hip fracture risk in adherent participants. However, a 2015 BMJ meta-analysis by Bolland et al. raised concerns about potential cardiovascular risks with calcium supplements exceeding 1,000mg/day, though this remains debated. Current consensus from the National Osteoporosis Foundation supports supplementation to reach 1,000-1,200mg total daily intake when dietary intake is insufficient, always paired with vitamin D.

References

  1. (). Calcium plus vitamin D supplementation and the risk of fractures. New England Journal of Medicine. DOI
  2. (). Calcium intake and risk of fracture: systematic review. BMJ. DOI
  3. (). Calcium intake and bone mineral density: systematic review and meta-analysis. BMJ. DOI