General Dosage
100-300mg daily with a meal containing fat
Maximum dose: 600mg/day (doses up to 1200mg have been used in Parkinson's trials without major safety concerns)
Coenzyme Q10 (CoQ10) Dosage Guide
This content is for informational purposes only and does not constitute medical advice. Consult your healthcare provider before starting any supplement. Full disclaimer
Dosage Recommendations
General recommendation: 100-300mg daily with a meal containing fat
Timing: With the largest meal of the day for best absorption; can split into 2 doses • Take with food for best absorption.
Dosage by Condition
| Condition | Recommended Dose | Evidence |
|---|---|---|
| General antioxidant/energy support | 100-200mg daily | Moderate |
| Heart failure (adjunct) | 300mg daily (as in Q-SYMBIO) | Moderate |
| Blood pressure support | 100-200mg daily | Moderate |
| Statin-induced myopathy | 100-200mg daily | Moderate |
Upper limit: 600mg/day (doses up to 1200mg have been used in Parkinson's trials without major safety concerns)
Timing & Absorption
With the largest meal of the day for best absorption; can split into 2 doses
Best taken with food for optimal absorption.
References
- Mortensen SA, Rosenfeldt F, Kumar A, et al. (2014). The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: results from Q-SYMBIO: a randomized double-blind trial. JACC: Heart Failure. DOI PubMed
- Rosenfeldt FL, Haas SJ, Krum H, et al. (2007). Coenzyme Q10 in the treatment of hypertension: a meta-analysis of the clinical trials. Journal of Human Hypertension. DOI PubMed
- Littarru GP, Tiano L (2007). Bioenergetic and antioxidant properties of coenzyme Q10: recent developments. Molecular Biotechnology. DOI PubMed
- Skarlovnik A, Janić M, Govedarica L, Šabovič M (2014). Coenzyme Q10 supplementation decreases statin-related mild-to-moderate muscle symptoms: a randomized clinical study. Medical Science Monitor. DOI PubMed