General Dosage
500-3000mg daily of fruiting body extract, standardized to >30% beta-glucans
Maximum dose: 3000mg/day from supplements (higher doses not well-studied)
Lion's Mane Dosage Guide
SC
DJP
This content is for informational purposes only and does not constitute medical advice. Consult your healthcare provider before starting any supplement. Full disclaimer
Dosage Recommendations
General recommendation: 500-3000mg daily of fruiting body extract, standardized to >30% beta-glucans
Timing: Consistent daily use for 4-8+ weeks to notice benefits; can be taken any time of day • Take with food for best absorption.
Dosage by Condition
| Condition | Recommended Dose | Evidence |
|---|---|---|
| Cognitive support | 1000-3000mg fruiting body extract daily | Moderate |
| Neuroprotection | 1000-3000mg daily, long-term use | Emerging |
| Anxiety/depression | 500-1000mg daily for 8+ weeks | Moderate |
| Gut health | 500-1000mg daily | Emerging |
Upper limit: 3000mg/day from supplements (higher doses not well-studied)
Timing & Absorption
Consistent daily use for 4-8+ weeks to notice benefits; can be taken any time of day
Best taken with food for optimal absorption.
References
- Mori K, Inatomi S, Ouchi K, Azumi Y, Tuchida T (2009). Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind placebo-controlled clinical trial. Phytotherapy Research. DOI PubMed
- Lai PL, Naidu M, Sabaratnam V, et al. (2013). Neurotrophic properties of the Lion's mane medicinal mushroom, Hericium erinaceus. International Journal of Medicinal Mushrooms. DOI PubMed
- Saitsu Y, Nishide A, Kikushima K, Shimizu K, Ohnuki K (2019). Improvement of cognitive functions by oral intake of Hericium erinaceus. Biomedical Research. DOI PubMed