Evidence Level
Shilajit research has accelerated in the last decade. The most significant clinical finding comes from Pandit et al. (2016, n=96, randomized double-blind placebo-controlled), which demonstrated 250mg PrimaVie shilajit twice daily for 90 days significantly increased total testosterone (+20.4%), free testosterone (+19.1%), and DHEA levels in healthy men aged 45-55. For mitochondrial function, Bhattacharyya et al. (2009) showed shilajit enhanced CoQ10 effectiveness by improving electron transport chain efficiency — making it a logical pairing with CoQ10 supplements. Safety studies by Velmurugan et al. (2012) confirmed purified shilajit at 2g/day for 45 days did not alter liver, kidney, or hematological markers. The primary safety concern remains heavy metal contamination in unpurified products.