We evaluated Vitamin K2 supplements across K2 form (MK-7 vs MK-4), dose, Vitamin D inclusion, third-party testing, and value. Our picks prioritize the long-acting MK-7 form for daily convenience and clinical evidence.
Best Vitamin K2 Supplements (2026)
· Updated April 2026
Lab Tested, Evidence Ranked
This content is for informational purposes only and does not constitute medical advice. Statements about dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary — consult your healthcare provider before starting any supplement. Full disclaimer
Our Verdict
The best Vitamin K2 supplement delivers MK-7 at 100-200mcg per capsule with high bioavailability, ideally paired with Vitamin D for synergistic bone and cardiovascular support.
Best By Category
The best vitamin K2 supplement delivers 100-200mcg of MK-7 (menaquinone-7) daily, ideally from natural fermented...
The best vitamin K2 supplement delivers 100-200mcg of MK-7 (menaquinone-7) daily, ideally from natural fermented sources with documented stability. MK-7 has a 72-hour half-life versus MK-4s 1-hour; pair with vitamin D3 (1,000-5,000 IU) for bone and cardiovascular synergy.
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How We Chose These Products
Products are ranked using our published scoring methodology — evidence strength, dose adequacy, ingredient form, third-party testing signals, value, and clean-label factors are weighted across the 5 criteria below. Commercial relationships do not determine our editorial rankings.
K2 Form
30%MK-7 is the preferred form for daily supplementation due to its 72-hour half-life, allowing once-daily dosing. MK-4 has a 6-hour half-life and requires multiple daily doses (typically 15mg 3x/day). Full-spectrum products offering both earn top marks.
Dose Adequacy
25%MK-7: 100-200mcg daily for bone and cardiovascular support. MK-4: 15mg 3x/day (45mg total) for bone density (Japanese clinical dose). Products should meet evidence-based dose thresholds.
Vitamin D Synergy
20%Vitamin K2 and D3 work synergistically — D3 increases calcium absorption while K2 directs calcium to bones and away from arteries. Combined products offer convenience and better outcomes.
Third-Party Testing
15%Independent verification of K2 form and potency. Important because MK-7 is expensive to produce and adulteration with cheaper K1 or MK-4 has been documented.
Value
10%Cost per serving relative to K2 form, dose, and additional ingredients. MK-7 costs more than MK-4 per microgram but requires far less frequent dosing.

Innovix Labs Full Spectrum Vitamin K2
InnovixLabs
7,457 Amazon reviews
The only product in the category delivering both MK-4 and MK-7 forms. MK-7 provides long-acting baseline coverage (72-hour half-life), while MK-4 offers tissue-specific benefits in brain, pancreas, and reproductive organs. Soy-free formulation in an oil-based softgel for fat-soluble absorption.
Pros
- Full spectrum: MK-4 + MK-7 combined
- Oil-based softgel for absorption
- Soy-free formula
Cons
- MK-4 dose below clinical threshold
- No vitamin D included
Quick Comparison





| # | Product | Best For | Ingredient & Dose | Form & Testing | Price | Rating | |
|---|---|---|---|---|---|---|---|
| 1 | ![]() Innovix Labs Full Spectrum Vitamin K2 #1 Top Pick 7,457 Amazon reviews | full-spectrum K2 with both MK-4 and MK-7 | MK-4 (500mcg) + MK-7 (100mcg) 500mcg MK-4 + 100mcg MK-7 per softgel | Softgel 90 Softgels Third-Party Tested | $26.95 $0.30/serving | 9.1/10 | |
| 2 | ![]() Life Extension Super K 1,585 Amazon reviews | comprehensive vitamin K formula with all three K forms | K1 (1500mcg) + MK-4 (1000mcg) + MK-7 (100mcg) 1500mcg K1 + 1000mcg MK-4 + 100mcg MK-7 per softgel | Softgel Third-Party Tested | $12.95 $0.14/serving | 9/10 | |
| 3 | ![]() NOW Foods MK-7 100mcg 8,359 Amazon reviews | value MK-7 supplement | Vitamin K2 as MK-7 100mcg MK-7 per capsule | Veg Capsule GMP Certified, Third-Party Tested | $10.00 $0.08/serving | 8.7/10 | |
| 4 | ![]() Sports Research Vitamin K2 MK-7 100mcg with Coconut MCT Oil 13,973 Amazon reviews | Bone and cardiovascular health — especially those pairing with Vitamin D3 who need K2 to direct calcium properly | Vitamin K2 (as Menaquinone-7 / MK-7) 100mcg from fermented chickpeas + Coconut MCT Oil 100mcg Vitamin K2 as MK-7 per softgel, once daily | Softgel 60.0 Count Third-Party Tested | $17.95 $0.30/serving | 8.5/10 | |
| 5 | ![]() Jarrow Formulas MK-7 90mcg 5,097 Amazon reviews | Quality MK-7 softgel at a good price | Vitamin K2 as MK-7 90mcg MK-7 per softgel | Softgel 60 Servings Third-Party Tested | $16.99 $0.28/serving | 8.5/10 |
Detailed Reviews

InnovixLabs Full Spectrum Vitamin K2-90 Softgels with 600 mcg of Trans Form MK7 and MK4 - Supports General Health and Bone Strength - Soy and Gluten Free K2 Vitamin Supplement
InnovixLabs
7,457 Amazon reviews
The only product in the category delivering both MK-4 and MK-7 forms. MK-7 provides long-acting baseline coverage (72-hour half-life), while MK-4 offers tissue-specific benefits in brain, pancreas, and reproductive organs. Soy-free formulation in an oil-based softgel for fat-soluble absorption.
Pros
- Full spectrum: MK-4 + MK-7 combined
- Oil-based softgel for absorption
- Soy-free formula
- 100mcg MK-7 (clinically relevant dose)
Cons
- MK-4 dose below clinical threshold
- No vitamin D included
- Smaller brand recognition

Super K with Advanced K2 Complex - 90 ct
Life Extension
1,585 Amazon reviews
The most comprehensive vitamin K formula available — combines K1, MK-4, and MK-7 in a single softgel with an oil base. K1 supports coagulation, MK-4 targets bone and brain tissue, MK-7 provides long-acting cardiovascular protection. Excellent value for a three-form formula.
Pros
- All three K forms: K1 + MK-4 + MK-7
- Oil-based softgel
- Excellent value at $0.22/serving
- Research-driven formulation
Cons
- High K1 may interact with warfarin
- MK-4 dose below clinical threshold
- Complex multi-form formula

NOW Foods Supplements, MK-7 Vitamin K-2 100 mcg, Cardiovascular Support*, Supports Bone Health*, 60 Veg Capsules
NOW Foods
8,359 Amazon reviews
Delivers the clinically studied 100mcg MK-7 dose at an unbeatable $0.12/serving. GMP-certified and third-party tested. NOW Foods is one of the most established supplement brands. Simple, clean formula with no unnecessary additives.
Pros
- Best value at $0.12/serving
- GMP certified
- Clean single-ingredient formula
- Full 100mcg clinical dose
Cons
- Veg capsule (no oil base)
- No vitamin D
- MK-7 only (no MK-4)

Sports Research® Vitamin K2 as MK-7 100mcg with Coconut MCT Oil - 60 Veggie Softgels (2 Month Supply) Vegan Certified, Non-GMO Verified, Gluten & Soy Free
#2 Best Sellerin Vitamin K1 SupplementsSports Research
13,973 Amazon reviews
Sports Research uses chickpea-derived MK-7 to offer a soy-free K2 in a Vegan Certified PlantGel softgel — a genuine formulation advantage over the many soy-based K2 products on the market, enhanced further by the coconut MCT oil base.
Pros
- MK-7 form — the most bioavailable and longest half-life form of K2
- Sourced from fermented chickpeas, not soy (unlike most K2 supplements)
- Coconut MCT oil co-formulation enhances fat-soluble K2 absorption
- Vegan Certified PlantGel capsule — carrageenan-free and bovine-free
Cons
- 60-count/2-month supply priced at $17.95 — moderate value
- Contraindicated with warfarin — limits use for a significant patient population
- No Informed Sport or IFOS-level certification — third-party tested but less specific

Jarrow Formulas MK-7 90 mcg - Bioactive Form of Vitamin K2-60 Servings (Softgels) - for Bone & Cardiovascular Health - Vitamin K2 MK-7 Dietary Supplement - Gluten-Free
Jarrow Formulas
5,097 Amazon reviews
Uses MenaQ7 — the most clinically studied form of MK-7 derived from natto fermentation. Oil-based softgel enhances absorption of fat-soluble vitamin K2. Jarrow Formulas is a trusted brand with strong quality control. Good balance of quality and value.
Pros
- MenaQ7 (most clinically studied MK-7)
- Oil-based softgel for absorption
- Trusted Jarrow Formulas brand
- Good value at $0.15/serving
Cons
- 90mcg (slightly below 100mcg standard)
- No vitamin D included
- Smaller bottle (60 softgels)
Pairs Well With
Frequently taken together based on complementary benefits

Vitamin D3
Sports Research Vitamin D3 + K2 (5000 IU)

Calcium
Integrative Therapeutics OsteoPrime Forte
How to Choose
Vitamin K2 comes in two main forms: MK-7 (menaquinone-7) and MK-4 (menaquinone-4). MK-7 has a 72-hour half-life, making it ideal for once-daily dosing at 100-200mcg. MK-4 has a 6-hour half-life and requires multiple daily doses at much higher amounts (15mg 3x/day in Japanese bone studies). For most people, MK-7 at 100mcg daily is the practical choice. Pairing K2 with vitamin D3 is synergistic — D3 increases calcium absorption, while K2 ensures calcium goes to bones rather than accumulating in arteries. If you take warfarin or other anticoagulants, consult your doctor before supplementing vitamin K in any form.
Ready to Buy?

Innovix Labs Full Spectrum Vitamin K2
The best Vitamin K2 supplement delivers MK-7 at 100-200mcg per capsule with high bioavailability, ideally paired with Vitamin D for synergistic bone and cardiovascular support.
Evidence:RCT (2013) · n=244 · high confidence[#1]. See full reference list below.Evidence level, dosage, side effects, and more →
Check how Vitamin K2 (MK-7) fits with your current stack — interactions, timing, and optimization →
Related Supplements
Bottom line: Most adults need vitamin D3 supplements — 42% are deficient. Take 1,000-4,000 IU daily with a fatty meal for immune, bone, and mood support.
Top picks →Bottom line: Get 1,000-1,200mg calcium daily from diet plus supplements if needed. Calcium citrate with vitamin D3 and K2 is the optimal bone-support stack.
Top picks →Related Conditions
Learn More
Frequently Asked Questions
What is the difference between MK-7 and MK-4?
What is the difference between MK-7 and MK-4?
MK-7 (from natto fermentation) has a 72-hour half-life, so 100-200mcg once daily maintains stable blood levels. MK-4 (found in animal foods) has a 6-hour half-life and requires 15mg three times daily for bone benefits. Most supplements use MK-7 for convenience and evidence-based dosing.
Should I take vitamin K2 with vitamin D?
Should I take vitamin K2 with vitamin D?
Yes, they work synergistically. Vitamin D increases calcium absorption from the gut, while K2 activates proteins (osteocalcin and matrix GLA protein) that direct calcium to bones and away from arteries. Taking D without K2 may increase arterial calcification risk over time.
Evidence:RCT (2013) · n=244 · high confidence[#1]. See full reference list below.Can I take vitamin K2 if I am on blood thinners?
Can I take vitamin K2 if I am on blood thinners?
If you take warfarin (Coumadin), consult your doctor before taking any vitamin K supplement. Vitamin K directly counteracts warfarin's mechanism. However, newer anticoagulants (DOACs like apixaban, rivaroxaban) do not interact with vitamin K, so K2 supplementation is generally safe with those medications.
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References
- RCTKnapen MH, Drummen NE, Smit E, Vermeer C, Theuwissen E (2013). Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women. Osteoporosis International. DOI PubMed
- ObservationalGeleijnse JM, Vermeer C, Grobbee DE, et al. (2004). Dietary intake of menaquinone is associated with a reduced risk of coronary heart disease: the Rotterdam Study. Journal of Nutrition. DOI PubMed