We evaluated vitamin K2 supplements across K2 form (MK-7 vs MK-4), dose, vitamin D inclusion, third-party testing, and value. Our picks prioritize the long-acting MK-7 form for daily convenience and clinical evidence.
Best Vitamin K2 Supplements (2026)
This content is for informational purposes only and does not constitute medical advice. Consult your healthcare provider before starting any supplement. Full disclaimer
Our Verdict
The best vitamin K2 supplement delivers MK-7 at 100-200mcg per capsule with high bioavailability, ideally paired with vitamin D for synergistic bone and cardiovascular support.
Best By Category
TL;DR — Quick Answer
The best vitamin K2 for most people is an MK-7 supplement at 100-200mcg daily. MK-7 has a much longer half-life than MK-4 (72 hours vs 6 hours), so once-daily dosing works. Innovix Labs Full Spectrum K2 covers both forms. For those also needing vitamin D, Life Extension Super K combines K1, MK-4, and MK-7.
Our recommendations are based on published research, not commission rates. Some links below are affiliate links — we may earn a commission at no extra cost to you. How we evaluate products
4+ products evaluated · Ratings based on published research, not commissions
Quick Comparison
#1Innovix Labs Full Spectrum Vitamin K2
9.1/10
Innovix Labs
Best for: Best full-spectrum K2 with both MK-4 and MK-7
MK-4 (500mcg) + MK-7 (100mcg) · 500mcg MK-4 + 100mcg MK-7 per softgel
Softgel · Third-Party Tested
$0.30
#2NOW Foods MK-7 100mcg
8.7/10
NOW Foods
Best for: Best value MK-7 supplement
Vitamin K2 as MK-7 · 100mcg MK-7 per capsule
Veg Capsule · GMP Certified, Third-Party Tested
$0.12
#3Life Extension Super K
9/10
Life Extension
Best for: Best comprehensive vitamin K formula with all three K forms
K1 (1500mcg) + MK-4 (1000mcg) + MK-7 (100mcg) · 1500mcg K1 + 1000mcg MK-4 + 100mcg MK-7 per softgel
Softgel · Third-Party Tested
$0.22
#4Jarrow Formulas MK-7 90mcg
8.5/10
Jarrow Formulas
Best for: Quality MK-7 softgel at a good price
Vitamin K2 as MK-7 · 90mcg MK-7 per softgel
Softgel · Third-Party Tested
$0.15
| # | Product | Best For | Ingredient & Dose | Form & Testing | Price | Rating | |
|---|---|---|---|---|---|---|---|
| 1 | Innovix Labs Full Spectrum Vitamin K2 Innovix Labs | Best full-spectrum K2 with both MK-4 and MK-7 | MK-4 (500mcg) + MK-7 (100mcg) 500mcg MK-4 + 100mcg MK-7 per softgel | Softgel Third-Party Tested | $0.30 | 9.1/10 | |
| 2 | NOW Foods MK-7 100mcg NOW Foods | Best value MK-7 supplement | Vitamin K2 as MK-7 100mcg MK-7 per capsule | Veg Capsule GMP Certified, Third-Party Tested | $0.12 | 8.7/10 | |
| 3 | Life Extension Super K Life Extension | Best comprehensive vitamin K formula with all three K forms | K1 (1500mcg) + MK-4 (1000mcg) + MK-7 (100mcg) 1500mcg K1 + 1000mcg MK-4 + 100mcg MK-7 per softgel | Softgel Third-Party Tested | $0.22 | 9/10 | |
| 4 | Jarrow Formulas MK-7 90mcg Jarrow Formulas | Quality MK-7 softgel at a good price | Vitamin K2 as MK-7 90mcg MK-7 per softgel | Softgel Third-Party Tested | $0.15 | 8.5/10 |
Detailed Reviews
Top Pick
1
Innovix Labs Full Spectrum Vitamin K2
Innovix Labs
9.1/10
$0.30/serving
Ingredient: MK-4 (500mcg) + MK-7 (100mcg)
Dose: 500mcg MK-4 + 100mcg MK-7 per softgel
Form: Softgel
Testing: Third-Party Tested
500mcg MK-4 + 100mcg MK-7 per softgelClinical range: 100-200mcg MK-7 daily
Clinical dose
Why we recommend it: The only product in the category delivering both MK-4 and MK-7 forms. MK-7 provides long-acting baseline coverage (72-hour half-life), while MK-4 offers tissue-specific benefits in brain, pancreas, and reproductive organs. Soy-free formulation in an oil-based softgel for fat-soluble absorption.
Ideal for: Best full-spectrum K2 with both MK-4 and MK-7
Not ideal for: Those wanting vitamin D included or seeking the lowest price.
Pros
- Full spectrum: MK-4 + MK-7 combined
- Oil-based softgel for absorption
- Soy-free formula
- 100mcg MK-7 (clinically relevant dose)
Cons
- MK-4 dose below clinical threshold
- No vitamin D included
- Smaller brand recognition
2
NOW Foods MK-7 100mcg
NOW Foods
8.7/10
$0.12/serving
Ingredient: Vitamin K2 as MK-7
Dose: 100mcg MK-7 per capsule
Form: Veg Capsule
Testing: GMP Certified, Third-Party Tested
100mcg MK-7 per capsuleClinical range: 100-200mcg MK-7 daily
Clinical dose
Why we recommend it: Delivers the clinically studied 100mcg MK-7 dose at an unbeatable $0.12/serving. GMP-certified and third-party tested. NOW Foods is one of the most established supplement brands. Simple, clean formula with no unnecessary additives.
Ideal for: Best value MK-7 supplement
Not ideal for: Those needing vitamin D or wanting a softgel with oil base.
Pros
- Best value at $0.12/serving
- GMP certified
- Clean single-ingredient formula
- Full 100mcg clinical dose
Cons
- Veg capsule (no oil base)
- No vitamin D
- MK-7 only (no MK-4)
3
Life Extension Super K
Life Extension
9/10
$0.22/serving
Ingredient: K1 (1500mcg) + MK-4 (1000mcg) + MK-7 (100mcg)
Dose: 1500mcg K1 + 1000mcg MK-4 + 100mcg MK-7 per softgel
Form: Softgel
Testing: Third-Party Tested
1500mcg K1 + 1000mcg MK-4 + 100mcg MK-7 per softgelClinical range: 100-200mcg MK-7 daily
Clinical dose
Why we recommend it: The most comprehensive vitamin K formula available — combines K1, MK-4, and MK-7 in a single softgel with an oil base. K1 supports coagulation, MK-4 targets bone and brain tissue, MK-7 provides long-acting cardiovascular protection. Excellent value for a three-form formula.
Ideal for: Best comprehensive vitamin K formula with all three K forms
Not ideal for: Those on warfarin or anticoagulants (high K1 dose may interfere).
Pros
- All three K forms: K1 + MK-4 + MK-7
- Oil-based softgel
- Excellent value at $0.22/serving
- Research-driven formulation
Cons
- High K1 may interact with warfarin
- MK-4 dose below clinical threshold
- Complex multi-form formula
4
Jarrow Formulas MK-7 90mcg
Jarrow Formulas
8.5/10
$0.15/serving
Ingredient: Vitamin K2 as MK-7
Dose: 90mcg MK-7 per softgel
Form: Softgel
Testing: Third-Party Tested
90mcg MK-7 per softgelClinical range: 100-200mcg MK-7 daily
Clinical dose
Why we recommend it: Uses MenaQ7 — the most clinically studied form of MK-7 derived from natto fermentation. Oil-based softgel enhances absorption of fat-soluble vitamin K2. Jarrow Formulas is a trusted brand with strong quality control. Good balance of quality and value.
Ideal for: Quality MK-7 softgel at a good price
Not ideal for: Those wanting 100mcg+ dose or added vitamin D.
Pros
- MenaQ7 (most clinically studied MK-7)
- Oil-based softgel for absorption
- Trusted Jarrow Formulas brand
- Good value at $0.15/serving
Cons
- 90mcg (slightly below 100mcg standard)
- No vitamin D included
- Smaller bottle (60 softgels)
How to Choose
Vitamin K2 comes in two main forms: MK-7 (menaquinone-7) and MK-4 (menaquinone-4). MK-7 has a 72-hour half-life, making it ideal for once-daily dosing at 100-200mcg. MK-4 has a 6-hour half-life and requires multiple daily doses at much higher amounts (15mg 3x/day in Japanese bone studies). For most people, MK-7 at 100mcg daily is the practical choice. Pairing K2 with vitamin D3 is synergistic — D3 increases calcium absorption, while K2 ensures calcium goes to bones rather than accumulating in arteries. If you take warfarin or other anticoagulants, consult your doctor before supplementing vitamin K in any form.
How We Evaluate
Every product is scored against these weighted criteria. Our ratings reflect clinical evidence and product quality, not commission rates.
K2 Form
30%MK-7 is the preferred form for daily supplementation due to its 72-hour half-life, allowing once-daily dosing. MK-4 has a 6-hour half-life and requires multiple daily doses (typically 15mg 3x/day). Full-spectrum products offering both earn top marks.
Dose Adequacy
25%MK-7: 100-200mcg daily for bone and cardiovascular support. MK-4: 15mg 3x/day (45mg total) for bone density (Japanese clinical dose). Products should meet evidence-based dose thresholds.
Vitamin D Synergy
20%Vitamin K2 and D3 work synergistically — D3 increases calcium absorption while K2 directs calcium to bones and away from arteries. Combined products offer convenience and better outcomes.
Third-Party Testing
15%Independent verification of K2 form and potency. Important because MK-7 is expensive to produce and adulteration with cheaper K1 or MK-4 has been documented.
Value
10%Cost per serving relative to K2 form, dose, and additional ingredients. MK-7 costs more than MK-4 per microgram but requires far less frequent dosing.
Frequently Asked Questions
What is the difference between MK-7 and MK-4?
What is the difference between MK-7 and MK-4?
MK-7 (from natto fermentation) has a 72-hour half-life, so 100-200mcg once daily maintains stable blood levels. MK-4 (found in animal foods) has a 6-hour half-life and requires 15mg three times daily for bone benefits. Most supplements use MK-7 for convenience and evidence-based dosing.
Should I take vitamin K2 with vitamin D?
Should I take vitamin K2 with vitamin D?
Yes, they work synergistically. Vitamin D increases calcium absorption from the gut, while K2 activates proteins (osteocalcin and matrix GLA protein) that direct calcium to bones and away from arteries. Taking D without K2 may increase arterial calcification risk over time.
Can I take vitamin K2 if I am on blood thinners?
Can I take vitamin K2 if I am on blood thinners?
If you take warfarin (Coumadin), consult your doctor before taking any vitamin K supplement. Vitamin K directly counteracts warfarin's mechanism. However, newer anticoagulants (DOACs like apixaban, rivaroxaban) do not interact with vitamin K, so K2 supplementation is generally safe with those medications.
References
- Knapen MH, Drummen NE, Smit E, Vermeer C, Theuwissen E (2013). Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women. Osteoporosis International. DOI PubMed
- Geleijnse JM, Vermeer C, Grobbee DE, et al. (2004). Dietary intake of menaquinone is associated with a reduced risk of coronary heart disease: the Rotterdam Study. Journal of Nutrition. DOI PubMed