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Best Vitamin K2 Supplements (2026)

· Updated April 2026

Lab Tested, Evidence Ranked

·
2,500+Clinical Studies Cited
5Vitamin K2 (MK-7) products evaluated

This content is for informational purposes only and does not constitute medical advice. Statements about dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary — consult your healthcare provider before starting any supplement. Full disclaimer

Our Verdict

The best Vitamin K2 supplement delivers MK-7 at 100-200mcg per capsule with high bioavailability, ideally paired with Vitamin D for synergistic bone and cardiovascular support.

Best By Category

Innovix Labs Full Spectrum Vitamin K2
#1Best Overall (Full Spectrum)
Innovix Labs Full Spectrum Vitamin K2
NOW Foods MK-7 100mcg
#3Best Value MK-7
NOW Foods MK-7 100mcg
Life Extension Super K
#2Best K2 + D3 Combo
Life Extension Super K

The best vitamin K2 supplement delivers 100-200mcg of MK-7 (menaquinone-7) daily, ideally from natural fermented...

The best vitamin K2 supplement delivers 100-200mcg of MK-7 (menaquinone-7) daily, ideally from natural fermented sources with documented stability. MK-7 has a 72-hour half-life versus MK-4s 1-hour; pair with vitamin D3 (1,000-5,000 IU) for bone and cardiovascular synergy.

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We evaluated Vitamin K2 supplements across K2 form (MK-7 vs MK-4), dose, Vitamin D inclusion, third-party testing, and value. Our picks prioritize the long-acting MK-7 form for daily convenience and clinical evidence.

As an Amazon Associate, we earn from qualifying purchases. Some links below are affiliate links — this doesn't affect our editorial independence or product ratings. How we evaluate products

How We Chose These Products

Products are ranked using our published scoring methodology — evidence strength, dose adequacy, ingredient form, third-party testing signals, value, and clean-label factors are weighted across the 5 criteria below. Commercial relationships do not determine our editorial rankings.

K2 Form

30%

MK-7 is the preferred form for daily supplementation due to its 72-hour half-life, allowing once-daily dosing. MK-4 has a 6-hour half-life and requires multiple daily doses (typically 15mg 3x/day). Full-spectrum products offering both earn top marks.

Dose Adequacy

25%

MK-7: 100-200mcg daily for bone and cardiovascular support. MK-4: 15mg 3x/day (45mg total) for bone density (Japanese clinical dose). Products should meet evidence-based dose thresholds.

Vitamin D Synergy

20%

Vitamin K2 and D3 work synergistically — D3 increases calcium absorption while K2 directs calcium to bones and away from arteries. Combined products offer convenience and better outcomes.

Third-Party Testing

15%

Independent verification of K2 form and potency. Important because MK-7 is expensive to produce and adulteration with cheaper K1 or MK-4 has been documented.

Value

10%

Cost per serving relative to K2 form, dose, and additional ingredients. MK-7 costs more than MK-4 per microgram but requires far less frequent dosing.

#1 Top Pick
Staff Pick
Innovix Labs Full Spectrum Vitamin K2 — view 1 of 5

Innovix Labs Full Spectrum Vitamin K2

InnovixLabs

7,457 Amazon reviews

9.1/10
4.7

The only product in the category delivering both MK-4 and MK-7 forms. MK-7 provides long-acting baseline coverage (72-hour half-life), while MK-4 offers tissue-specific benefits in brain, pancreas, and reproductive organs. Soy-free formulation in an oil-based softgel for fat-soluble absorption.

IngredientMK-4 (500mcg) + MK-7 (100mcg)
Dose500mcg MK-4 + 100mcg MK-7 per softgel
FormSoftgel
TestingThird-Party Tested
500mcg MK-4 + 100mcg MK-7 per softgelClinical range: 100-200 mcg MK-7 daily
Clinical dose
$0.30/serving$26.95 · 90 Softgels

Pros

  • Full spectrum: MK-4 + MK-7 combined
  • Oil-based softgel for absorption
  • Soy-free formula

Cons

  • MK-4 dose below clinical threshold
  • No vitamin D included

Quick Comparison

Innovix Labs Full Spectrum Vitamin K2 Softgel
#1Innovix Labs Full Spectrum Vitamin K2
9.1/10
InnovixLabs
#1 Top Pick
7,457 Amazon reviews
Best for: full-spectrum K2 with both MK-4 and MK-7
MK-4 (500mcg) + MK-7 (100mcg) · 500mcg MK-4 + 100mcg MK-7 per softgel
Softgel · Third-Party Tested
$26.95
$0.30/serving
Life Extension Super K Softgel
#2Life Extension Super K
9/10
Life Extension
1,585 Amazon reviews
Best for: comprehensive vitamin K formula with all three K forms
K1 (1500mcg) + MK-4 (1000mcg) + MK-7 (100mcg) · 1500mcg K1 + 1000mcg MK-4 + 100mcg MK-7 per softgel
Softgel · Third-Party Tested
$12.95
$0.14/serving
NOW Foods MK-7 100mcg Veg Capsule
#3NOW Foods MK-7 100mcg
8.7/10
NOW Foods
8,359 Amazon reviews
Best for: value MK-7 supplement
Vitamin K2 as MK-7 · 100mcg MK-7 per capsule
Veg Capsule · GMP Certified, Third-Party Tested
$10.00
$0.08/serving
Sports Research Vitamin K2 MK-7 100mcg with Coconut MCT Oil Softgel
#4Sports Research Vitamin K2 MK-7 100mcg with Coconut MCT Oil
8.5/10
Sports Research
13,973 Amazon reviews
Best for: Bone and cardiovascular health — especially those pairing with Vitamin D3 who need K2 to direct calcium properly
Vitamin K2 (as Menaquinone-7 / MK-7) 100mcg from fermented chickpeas + Coconut MCT Oil · 100mcg Vitamin K2 as MK-7 per softgel, once daily
Softgel · Third-Party Tested
$17.95
$0.30/serving
Jarrow Formulas MK-7 90mcg Softgel
#5Jarrow Formulas MK-7 90mcg
8.5/10
Jarrow Formulas
5,097 Amazon reviews
Best for: Quality MK-7 softgel at a good price
Vitamin K2 as MK-7 · 90mcg MK-7 per softgel
Softgel · Third-Party Tested
$16.99
$0.28/serving

Detailed Reviews

#1 Top Pick
Innovix Labs Full Spectrum Vitamin K2 — view 1 of 5

InnovixLabs Full Spectrum Vitamin K2-90 Softgels with 600 mcg of Trans Form MK7 and MK4 - Supports General Health and Bone Strength - Soy and Gluten Free K2 Vitamin Supplement

InnovixLabs

7,457 Amazon reviews

9.1/10
(7,457)

The only product in the category delivering both MK-4 and MK-7 forms. MK-7 provides long-acting baseline coverage (72-hour half-life), while MK-4 offers tissue-specific benefits in brain, pancreas, and reproductive organs. Soy-free formulation in an oil-based softgel for fat-soluble absorption.

IngredientMK-4 (500mcg) + MK-7 (100mcg)
Dose500mcg MK-4 + 100mcg MK-7 per softgel
FormSoftgel
TestingThird-Party Tested
500mcg MK-4 + 100mcg MK-7 per softgelClinical range: 100-200 mcg MK-7 daily
Clinical dose
$0.30/serving$26.95 · 90 Softgels
Ideal for: full-spectrum K2 with both MK-4 and MK-7
Not ideal for: Those wanting vitamin D included or seeking the lowest price.

Pros

  • Full spectrum: MK-4 + MK-7 combined
  • Oil-based softgel for absorption
  • Soy-free formula
  • 100mcg MK-7 (clinically relevant dose)

Cons

  • MK-4 dose below clinical threshold
  • No vitamin D included
  • Smaller brand recognition
Life Extension Super K — view 1 of 4

Super K with Advanced K2 Complex - 90 ct

Life Extension

1,585 Amazon reviews

9/10
(1,585)

The most comprehensive vitamin K formula available — combines K1, MK-4, and MK-7 in a single softgel with an oil base. K1 supports coagulation, MK-4 targets bone and brain tissue, MK-7 provides long-acting cardiovascular protection. Excellent value for a three-form formula.

IngredientK1 (1500mcg) + MK-4 (1000mcg) + MK-7 (100mcg)
Dose1500mcg K1 + 1000mcg MK-4 + 100mcg MK-7 per softgel
FormSoftgel
TestingThird-Party Tested
1500mcg K1 + 1000mcg MK-4 + 100mcg MK-7 per softgelClinical range: 100-200 mcg MK-7 daily
Clinical dose
$0.14/serving
Ideal for: comprehensive vitamin K formula with all three K forms
Not ideal for: Those on warfarin or anticoagulants (high K1 dose may interfere).

Pros

  • All three K forms: K1 + MK-4 + MK-7
  • Oil-based softgel
  • Excellent value at $0.22/serving
  • Research-driven formulation

Cons

  • High K1 may interact with warfarin
  • MK-4 dose below clinical threshold
  • Complex multi-form formula
NOW Foods MK-7 100mcg — view 1 of 5

NOW Foods Supplements, MK-7 Vitamin K-2 100 mcg, Cardiovascular Support*, Supports Bone Health*, 60 Veg Capsules

NOW Foods

8,359 Amazon reviews

8.7/10
(8,359)

Delivers the clinically studied 100mcg MK-7 dose at an unbeatable $0.12/serving. GMP-certified and third-party tested. NOW Foods is one of the most established supplement brands. Simple, clean formula with no unnecessary additives.

IngredientVitamin K2 as MK-7
Dose100mcg MK-7 per capsule
FormVeg Capsule
TestingGMP Certified, Third-Party Tested
100mcg MK-7 per capsuleClinical range: 100-200 mcg MK-7 daily
Therapeutic dose
$0.08/serving
Ideal for: value MK-7 supplement
Not ideal for: Those needing vitamin D or wanting a softgel with oil base.

Pros

  • Best value at $0.12/serving
  • GMP certified
  • Clean single-ingredient formula
  • Full 100mcg clinical dose

Cons

  • Veg capsule (no oil base)
  • No vitamin D
  • MK-7 only (no MK-4)
Sports Research Vitamin K2 MK-7 100mcg with Coconut MCT Oil — view 1 of 5

Sports Research® Vitamin K2 as MK-7 100mcg with Coconut MCT Oil - 60 Veggie Softgels (2 Month Supply) Vegan Certified, Non-GMO Verified, Gluten & Soy Free

#2 Best Sellerin Vitamin K1 Supplements

Sports Research

13,973 Amazon reviews

8.5/10
(13,973)

Sports Research uses chickpea-derived MK-7 to offer a soy-free K2 in a Vegan Certified PlantGel softgel — a genuine formulation advantage over the many soy-based K2 products on the market, enhanced further by the coconut MCT oil base.

IngredientVitamin K2 (as Menaquinone-7 / MK-7) 100mcg from fermented chickpeas + Coconut MCT Oil
Dose100mcg Vitamin K2 as MK-7 per softgel, once daily
FormSoftgel
TestingThird-Party Tested
100mcg Vitamin K2 as MK-7 per softgel, once dailyClinical range: 100-200 mcg MK-7 daily
Therapeutic dose
$0.30/serving$17.95 · 60.0 Count
Ideal for: Bone and cardiovascular health — especially those pairing with Vitamin D3 who need K2 to direct calcium properly
Not ideal for: Anyone on warfarin or other vitamin K-antagonist anticoagulants — K2 directly conflicts with these medications

Pros

  • MK-7 form — the most bioavailable and longest half-life form of K2
  • Sourced from fermented chickpeas, not soy (unlike most K2 supplements)
  • Coconut MCT oil co-formulation enhances fat-soluble K2 absorption
  • Vegan Certified PlantGel capsule — carrageenan-free and bovine-free

Cons

  • 60-count/2-month supply priced at $17.95 — moderate value
  • Contraindicated with warfarin — limits use for a significant patient population
  • No Informed Sport or IFOS-level certification — third-party tested but less specific
Jarrow Formulas MK-7 90mcg — view 1 of 5

Jarrow Formulas MK-7 90 mcg - Bioactive Form of Vitamin K2-60 Servings (Softgels) - for Bone & Cardiovascular Health - Vitamin K2 MK-7 Dietary Supplement - Gluten-Free

Jarrow Formulas

5,097 Amazon reviews

8.5/10
(5,097)

Uses MenaQ7 — the most clinically studied form of MK-7 derived from natto fermentation. Oil-based softgel enhances absorption of fat-soluble vitamin K2. Jarrow Formulas is a trusted brand with strong quality control. Good balance of quality and value.

IngredientVitamin K2 as MK-7
Dose90mcg MK-7 per softgel
FormSoftgel
TestingThird-Party Tested
90mcg MK-7 per softgelClinical range: 100-200 mcg MK-7 daily
Partial dose
$0.28/serving$16.99 · 60 Servings
Ideal for: Quality MK-7 softgel at a good price
Not ideal for: Those wanting 100mcg+ dose or added vitamin D.

Pros

  • MenaQ7 (most clinically studied MK-7)
  • Oil-based softgel for absorption
  • Trusted Jarrow Formulas brand
  • Good value at $0.15/serving

Cons

  • 90mcg (slightly below 100mcg standard)
  • No vitamin D included
  • Smaller bottle (60 softgels)

Pairs Well With

Frequently taken together based on complementary benefits

Sports Research Vitamin D3 + K2 (5000 IU) Softgel with coconut oil
(51,867)$0.07/serving
Integrative Therapeutics OsteoPrime Forte Capsule

Calcium

Integrative Therapeutics OsteoPrime Forte

4 capsules daily with a meal (can be split as 2 capsules twice daily with a meal)
(369)$0.23/serving

How to Choose

Vitamin K2 comes in two main forms: MK-7 (menaquinone-7) and MK-4 (menaquinone-4). MK-7 has a 72-hour half-life, making it ideal for once-daily dosing at 100-200mcg. MK-4 has a 6-hour half-life and requires multiple daily doses at much higher amounts (15mg 3x/day in Japanese bone studies). For most people, MK-7 at 100mcg daily is the practical choice. Pairing K2 with vitamin D3 is synergistic — D3 increases calcium absorption, while K2 ensures calcium goes to bones rather than accumulating in arteries. If you take warfarin or other anticoagulants, consult your doctor before supplementing vitamin K in any form.

Ready to Buy?

Innovix Labs Full Spectrum Vitamin K2

Innovix Labs Full Spectrum Vitamin K2

9.1/10$0.30/servingBest for: full-spectrum K2 with both MK-4 and MK-7

The best Vitamin K2 supplement delivers MK-7 at 100-200mcg per capsule with high bioavailability, ideally paired with Vitamin D for synergistic bone and cardiovascular support.

Evidence:RCT (2013) · n=244 · high confidence[#1]. See full reference list below.
Read Our Full Vitamin K2 (MK-7) Research Guide

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Frequently Asked Questions

What is the difference between MK-7 and MK-4?

MK-7 (from natto fermentation) has a 72-hour half-life, so 100-200mcg once daily maintains stable blood levels. MK-4 (found in animal foods) has a 6-hour half-life and requires 15mg three times daily for bone benefits. Most supplements use MK-7 for convenience and evidence-based dosing.

Should I take vitamin K2 with vitamin D?

Yes, they work synergistically. Vitamin D increases calcium absorption from the gut, while K2 activates proteins (osteocalcin and matrix GLA protein) that direct calcium to bones and away from arteries. Taking D without K2 may increase arterial calcification risk over time.

Evidence:RCT (2013) · n=244 · high confidence[#1]. See full reference list below.

Can I take vitamin K2 if I am on blood thinners?

If you take warfarin (Coumadin), consult your doctor before taking any vitamin K supplement. Vitamin K directly counteracts warfarin's mechanism. However, newer anticoagulants (DOACs like apixaban, rivaroxaban) do not interact with vitamin K, so K2 supplementation is generally safe with those medications.

Continue Reading

References

  1. RCTKnapen MH, Drummen NE, Smit E, Vermeer C, Theuwissen E (2013). Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women. Osteoporosis International. DOI PubMed
  2. ObservationalGeleijnse JM, Vermeer C, Grobbee DE, et al. (2004). Dietary intake of menaquinone is associated with a reduced risk of coronary heart disease: the Rotterdam Study. Journal of Nutrition. DOI PubMed