Best Hemp Seed Oil Supplements (2026 Review)

Q: Is hemp seed oil the same as CBD oil?

No, they are completely different products. Hemp seed oil is cold-pressed from hemp seeds and contains zero cannabinoids, meaning no THC and no CBD. It is a nutritional oil valued for its omega fatty acids and GLA. CBD oil is extracted from hemp flowers, leaves, and stalks and contains cannabidiol. All products in this comparison are pure hemp seed oil with no cannabinoid content.

Q: Will hemp seed oil show up on a drug test?

No. Hemp seed oil contains no THC (the psychoactive cannabinoid that drug tests detect) and no other cannabinoids. It is a food-grade oil pressed from seeds only. Drug test concerns apply to full-spectrum CBD products, not hemp seed oil. However, always buy from reputable manufacturers to ensure no cross-contamination during processing.

Q: What is GLA and why does it matter in hemp seed oil?

GLA (gamma-linolenic acid) is an omega-6 fatty acid that, unlike most omega-6s, has anti-inflammatory properties. Your body converts GLA into DGLA, which produces anti-inflammatory prostaglandins. Hemp seed oil typically contains 2-4% GLA. A 2005 randomized controlled trial found that dietary hemp seed oil improved eczema symptoms, likely through this GLA pathway. Few common plant oils contain meaningful GLA amounts, making hemp seed oil unique.

Q: What is the ideal omega-6 to omega-3 ratio?

Research suggests a ratio between 2:1 and 4:1 is optimal for reducing inflammation and supporting cardiovascular health. Hemp seed oil naturally provides approximately a 3:1 ratio, which falls right in this optimal range. For comparison, the typical Western diet has a ratio of 15:1 to 20:1, which promotes chronic inflammation. This naturally balanced ratio is one of hemp seed oil's primary nutritional advantages.

Q: How much hemp seed oil should I take daily?

For general nutritional support, 1000-2000mg daily (1-2 softgels) is a standard maintenance dose. The Callaway 2005 eczema study used approximately 30mL of liquid hemp seed oil daily, which translates to roughly 2-3 softgels of a 1400mg product. Start with one softgel daily and increase gradually. Hemp seed oil is a food oil with a strong safety profile, so higher doses are generally well tolerated.

Q: Should I choose softgels or liquid hemp seed oil?

Softgels offer better protection against oxidation (the sealed capsule limits air exposure), precise dosing, and convenience. Liquid hemp seed oil is more economical per gram and allows higher daily doses more easily, but it must be refrigerated after opening and used within weeks. For supplementation purposes, softgels are generally more practical. For cooking or adding to smoothies, liquid oil is better.

Q: Can vegans take hemp seed oil supplements?

Most hemp seed oil supplements use gelatin softgels, which are not vegan. The DEVA Vegan Virgin Hemp Seed Oil Capsules in this comparison use a plant cellulose capsule shell, making them suitable for strict vegans. Alternatively, liquid hemp seed oil (sold in bottles) is inherently vegan. Always check the capsule material if vegan compliance matters to you.

Q: Does cold-pressed really matter for hemp seed oil?

Yes, significantly. Hemp seed oil's key fatty acids (omega-3 ALA, GLA, and SDA) are polyunsaturated and sensitive to heat. Cold-pressing preserves these delicate fats, along with natural vitamin E and other micronutrients. Heat extraction or hexane-solvent processing can oxidize omega-3s and destroy GLA. Products labeled 'cold-pressed' and 'hexane-free' (like NOW Foods and DEVA) retain the full nutritional profile that makes hemp seed oil beneficial.

Q: NOW Foods Hemp Seed Oil 1000mg: Are there any potential interactions with medications?

NOW Foods Hemp Seed Oil 1000mg contains Cold-pressed hemp seed oil (Cannabis sativa). As with any hemp seed oil supplement, consult your healthcare provider if you take prescription medications, especially blood thinners, blood pressure medications, or immunosuppressants. NOW Foods recommends consulting a doctor before use if you are on medication.

Q: NOW Foods Hemp Seed Oil 1000mg: Are there any side effects from long-term use?

At 1000mg (1 softgel), NOW Foods Hemp Seed Oil 1000mg provides a clinically effective dose within the studied range of 1000-3000mg hemp seed oil daily. Long-term use at recommended doses is generally well-tolerated based on available research. Discontinue and consult a healthcare provider if you experience adverse effects.

Sarah Chen

Best Hemp Seed Oil Supplements (2026)

Lab Tested, Evidence Ranked

Sarah Chen·MS Clinical Nutrition, CNS

Reviewed byDr. James Park·PharmD, BCPS

Published Apr 1, 2026

This content is for informational purposes only and does not constitute medical advice. Consult your healthcare provider before starting any supplement. Full disclaimer

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We evaluated hemp seed oil supplements (NOT CBD oil) on omega-6:omega-3 ratio, GLA content, cold-pressed extraction, third-party testing, and value per serving. Hemp seed oil is prized for its optimal fatty acid profile and GLA content, not cannabinoids.

As an Amazon Associate, we earn from qualifying purchases. Some links below are affiliate links — this doesn't affect our editorial independence or product ratings. How we evaluate products

5+ products evaluated · Ratings based on published research, not commissions

How We Evaluate

Every product is scored against these weighted criteria. Our ratings reflect clinical evidence and product quality, not commission rates.

Omega-6:Omega-3 Ratio

25%

Hemp seed oil's signature benefit is its approximately 3:1 omega-6 to omega-3 ratio, considered optimal for human health. Products maintaining this ratio through gentle extraction score highest.

GLA Content

25%

Gamma-linolenic acid (GLA) is the key anti-inflammatory omega-6 in hemp seed oil. GLA converts to DGLA, which competes with arachidonic acid to reduce inflammatory eicosanoids.

Cold-Pressed / Organic Quality

20%

Cold-pressing preserves heat-sensitive fatty acids and prevents oxidation. Hexane-free extraction avoids solvent residues. Organic sourcing reduces pesticide exposure.

Third-Party Testing

15%

Independent testing verifies fatty acid profile, absence of heavy metals, and confirms no THC/CBD contamination. GMP certification ensures manufacturing quality.

Value per Serving

15%

Cost per softgel adjusted for dose and count. Higher-dose products (1400mg) and larger counts (180ct) offer better long-term value.

References

Callaway J, Schwab U, Harvima I, et al. (2005). Efficacy of dietary hempseed oil in patients with atopic dermatitis. Journal of Dermatological Treatment. DOI PubMed
Schwab US, Callaway JC, Erkkila AT, et al. (2006). Effects of hempseed and flaxseed oils on the profile of serum lipids, serum total and lipoprotein lipid concentrations and haemostatic factors. European Journal of Nutrition. DOI PubMed
Richard MN, Bhattacharjee J, Hardy DB, et al. (2008). Hydroxyeicosatetraenoic acids generated by GLA-enriched diet modulate immune function. Prostaglandins, Leukotrienes and Essential Fatty Acids. DOI PubMed
Deferne JL, Pate DW (1996). Hemp seed oil: a source of valuable essential fatty acids. Journal of the International Hemp Association.
Simopoulos AP (2002). The importance of the ratio of omega-6/omega-3 essential fatty acids. Biomedicine & Pharmacotherapy. DOI PubMed
Leizer C, Ribnicky D, Poulev A, et al. (2000). The composition of hemp seed oil and its potential as an important source of nutrition. Journal of Nutraceuticals, Functional & Medical Foods. DOI
Kriese U, Schumann E, Weber WE, et al. (2004). Oil content, tocopherol composition and fatty acid patterns of the seeds of 51 Cannabis sativa L. genotypes. Euphytica. DOI
Oomah BD, Busson M, Godfrey DV, Drover JCG (2002). Characteristics of hemp (Cannabis sativa L.) seed oil. Food Chemistry. DOI
Teh SS, Birch J (2013). Physicochemical and quality characteristics of cold-pressed hemp, flax and canola seed oils. Journal of Food Composition and Analysis. DOI