Integrative Therapeutics
Integrative Therapeutics is a clinical-grade supplement brand founded in 1979 in Green Bay, Wisconsin, and now a division of Schwabe Extracta (acquired 2014). The brand was built for licensed healthcare professionals — physicians, naturopaths, and functional medicine practitioners — and remains one of the most trusted practitioner-channel lines in North America. Core categories include adrenal/stress support, gastrointestinal health, metabolic and cardiovascular function, and immune regulation. Flagship products include SBI Protect (secretory IgG), Cortisol Manager, Berberine 500, and the Pro-Flora MAX probiotic line. All formulations are GMP certified, carry clean-label sourcing commitments, and are grounded in peer-reviewed science rather than marketing trends. With 93 SKUs, Integrative Therapeutics represents one of the broadest clinical-grade catalogs available to consumers through practitioner recommendation.
Integrative Therapeutics earns Science-Verified designation for its clinical-grade, practitioner-backed formulations...
Integrative Therapeutics earns Science-Verified designation for its clinical-grade, practitioner-backed formulations with disclosed ingredient dosing, GMP-certified manufacturing, and a 45-year track record of healthcare professional trust.
Browse Products
Integrative Therapeutics Zinc Chelate
1 capsule per serving; 100 servings per bottle per capsule · Zinc bisglycinate (chelated zinc)
Integrative Therapeutics Zinc Chelate delivers zinc bisglycinate — a chelated form of zinc recognized for superior bioavailability compared to zinc oxide or zinc sulfate. Each capsule provides foundational immune support and antioxidant protection through zinc's role in white blood cell activation and free radical neutralization. Formulated without wheat, gluten, soy, dairy, or artificial additives. Manufactured under GMP standards since 1979.
IT Vitamin C with Quercetin
Vitamin C with quercetin and bioflavonoids per 2-capsule serving (180 capsules, 90 servings) per capsule · Vitamin C + Quercetin + Citrus Bioflavonoids
Clinical-grade vitamin C capsule combining ascorbic acid with quercetin and citrus bioflavonoids for immune and antioxidant support. Vegan, gluten-free.
IT Fiber Formula Capsules (120ct / 24srv)
5 capsules per serving; 24 servings per 120-count bottle per capsule · Dietary fiber blend (True Dispersion Technology)
120 capsules using True Dispersion Technology to deliver dietary fiber for colon function and digestive health. 270 reviews at 4.5 stars. Dairy-free and vegan.
IT Blue Heron Colon Support
6 capsules per serving (120 capsules, 20 servings) per capsule · Psyllium + Flax + Rice Bran + Triphala + Probiotic blend
Gentle colon support blend with psyllium, flax, rice bran, Triphala, and probiotics for intestinal and gastrointestinal health. Dairy-free. 120 capsules (20 servings).
IT Similase Sensitive Stomach (180ct / 90 Servings)
2 capsules per serving; 90 servings per 180-count bottle per capsule · Microbial digestive enzymes + marshmallow, slippery elm, licorice root, gamma-oryzanol
180-capsule digestive enzyme formula with marshmallow, slippery elm, licorice root, gamma-oryzanol, and microbial enzymes for sensitive GI tract support.
IT Pure Omega HP Fish Oil Softgels
375 mg EPA + 125 mg DHA + 75 mg other omega-3s per softgel (575 mg total omega-3 per serving) per softgel · EPA (375 mg) + DHA (125 mg) per softgel
High-purity omega-3 softgels delivering 375 mg EPA + 125 mg DHA per capsule. Rosemary preservation, molecular distillation, third-party tested. 120-count bottle.
Integrative Therapeutics Curcumax Pro
2 tablets per serving, 30 servings per tablet · Meriva Curcumin Phytosome
Clinically validated Meriva curcumin paired with ApresFlex boswellia and bioavailable quercetin for daily movement and discomfort support.
Integrative Therapeutics UBQH Ubiquinol CoQ10 100mg
1 softgel per serving, 100 mg ubiquinol (60 softgels, 60 servings) per softgel · Ubiquinol (Reduced CoQ10) 100 mg
Clinical-grade 100 mg ubiquinol (reduced, active CoQ10) softgel formulated for adults requiring higher bioavailability CoQ10 — particularly older individuals and statin users for whom standard CoQ10 conversion may be impaired. Free from salt, wheat, soy, and dairy.
IT Calcium D-Glucarate
3 capsules per serving (90 capsules, 30 servings) per capsule · Calcium D-Glucarate
Calcium D-glucarate capsule supporting detoxification systems, estrogen metabolism, and healthy immune function. Gluten-free, dairy-free. 90 capsules (30 servings).
IT GABA 750mg Capsules (60ct)
1 capsule once or twice daily; dose per capsule not disclosed in scrape data per capsule · GABA (gamma-aminobutyric acid)
Single-ingredient GABA (gamma-aminobutyric acid) capsules from Integrative Therapeutics for brain nerve function and neurochemical balance support in adults.
Integrative Therapeutics ProThrivers Wellness Sleep
1 capsule per serving (60 capsules, 60 servings) per capsule · Melatonin + Magnesium Bisglycinate + Suntheanine L-Theanine + Magnolia Bark Extract
Clinical-grade sleep support formula designed in collaboration with naturopathic oncology expert Dr. Lise Alschuler. Combines melatonin, magnesium bisglycinate, Suntheanine L-theanine, and magnolia bark extract to support sleep onset, sleep cycle health, and restful sleep. Vegan, gluten-free, and dairy-free.
IT Pure Omega Ultra HP 1392 mg Softgels
1392 mg total omega-3 per softgel; specific EPA and DHA mg per softgel from label (ultra-HP concentrate formula) per softgel · Ultra-concentrated EPA + DHA per 1392 mg softgel
Ultra-high-potency omega-3 softgel delivering 1392 mg total omega-3 per capsule from sustainably sourced anchovy, jack mackerel, sardine, and mackerel. Rosemary-preserved, GMP.
IT V Clear EPs 7630 Drops (1 fl oz)
Concentrated drops; 1 fl oz bottle, for ages 13+ per liquid · Pelargonium sidoides 1X (EPs 7630)
1 fl oz concentrated drops with Pelargonium sidoides 1X (EPs 7630) for throat, nasal, and bronchial comfort during the common cold — backed by 20+ clinical studies.
Integrative Therapeutics Neurologix
2 capsules per serving; 14 servings per 28-count bottle per capsule · Cognizin CDP-Choline + Saffron extract + Spearmint extract (Neumentix)
Neurologix is a multi-ingredient nootropic from Integrative Therapeutics combining Cognizin CDP-choline, saffron extract, and spearmint extract. It is designed to support brain energy metabolism, sustained concentration, and positive outlook without stimulants. Each serving includes clinically validated Cognizin citicoline and standardized saffron extract for mood and cognitive support. Vegan, gluten-free, and formulated under GMP standards since 1979.
IT Bio-Zyme Pancreatic Enzyme 200ct
2 tablets per serving (100 servings per bottle) per tablet · Undiluted Pancreatic Enzymes (Protease, Lipase, Amylase)
Undiluted pancreatic enzyme complex delivering protease, lipase, and amylase activity for comprehensive digestive and systemic enzyme support.
IT 5-HTP 100mg
1 capsule per serving, 100mg 5-HTP (60 capsules, 60 servings) per capsule · 5-HTP (L-5-Hydroxytryptophan) 100mg
Clinical-grade 5-HTP 100mg from Griffonia simplicifolia seeds supporting mood outlook and restful sleep. Vegan, gluten-free, dairy-free. 60 capsules.
Integrative Therapeutics Pro-Som
4 capsules per serving; 15 servings per 60-capsule bottle per capsule · Suntheanine L-Theanine + Magnesium + Magnolia Bark + Theracurmin (Bioavailable Curcumin)
Melatonin-free sleep support capsule combining clinically validated Suntheanine L-theanine with magnesium, magnolia bark extract, and Theracurmin (bioavailable curcumin) to support sleep quality, reduce waking after sleep onset, and promote relaxation without hormonal intervention. 60 capsules per bottle (15 servings at 4 capsules/night). Dairy-free, gluten-free, soy-free. GMP-manufactured by Integrative Therapeutics since 1979.
IT Indolplex DIM 240mg Capsules (60ct / 30srv)
240mg BR-DIM per serving (2 capsules); 30 servings per 60-count bottle per capsule · BR-DIM (bioavailable diindolylmethane) 240mg per serving
60 capsules of BR-DIM (bioavailable diindolylmethane) at 240mg per 2-capsule serving for estrogen metabolism and hormone balance. 153 reviews at 4.5 stars.
IT Betaine HCl with Pepsin
2 capsules per serving (250 capsules, 125 servings) per capsule · Betaine HCl + Pepsin
Betaine hydrochloride plus pepsin formula supporting healthy stomach acidity, gastric function, and protein digestion. Dairy-free. 250 capsules (125 servings).
IT Similase Lipo Digestive Enzymes (90ct)
2 capsules per serving; 45 servings per 90-count bottle per capsule · Multi-enzyme blend with enhanced lipase activity
Broad-spectrum digestive enzyme capsules with added lipase activity for fat and fat-soluble nutrient digestion. 90 capsules, 45 servings, dairy-free and vegan.
IT NutriVitamin Enzyme Complex
3 capsules per serving (180 capsules, 60 servings) per capsule · Multivitamin complex + Digestive Enzymes + Vitamin C + Vitamin E + Selenium
Clinical-grade multivitamin and mineral complex with digestive enzymes, vitamin C, E, and selenium. Iron-free formula designed for ongoing nutritional maintenance.
IT Pure Omega Liquid Fish Oil Lemon
2300 mg total omega-3 per serving: 1500 mg EPA + 500 mg DHA + 300 mg other omega-3s per liquid · EPA (1500 mg) + DHA (500 mg) per serving
Lemon-flavoured liquid fish oil delivering 2300 mg omega-3 per serving — 1500 mg EPA, 500 mg DHA, 300 mg other omegas. Molecular distillation, third-party tested.
IT Detoxification Factors
2 capsules per serving (60 capsules, 30 servings) per capsule · Vitamins A, C, E + 30+ ingredient detox complex
30+ ingredient clinical liver support capsule targeting phase I and II detoxification pathways with antioxidant vitamins and botanical cofactors. Dairy-free.
IT Flush-Free Niacin
1 capsule per serving, inositol hexaniacinate form (60 capsules, 60 servings) per capsule · Inositol hexaniacinate (flush-free niacin / vitamin B3)
Flush-free niacin as inositol hexaniacinate for cellular energy support without the skin flushing of standard niacin. Vegan, gluten-free, dairy-free. 60 capsules.
Frequently Asked Questions
Do I need a doctor to buy Integrative Therapeutics products?
Do I need a doctor to buy Integrative Therapeutics products?
Traditionally, Integrative Therapeutics sold exclusively through licensed healthcare professionals (physicians, naturopaths, functional medicine practitioners). Today, most SKUs are also available through Amazon and third-party retailers without a prescription. However, the brand still recommends professional supervision, especially for condition-specific products like Cortisol Manager or SBI Protect, because dosing and selection decisions benefit from clinical guidance.
Is Integrative Therapeutics a reputable brand?
Is Integrative Therapeutics a reputable brand?
Yes — Integrative Therapeutics has a 45-year track record as a practitioner-trusted brand. Since its 1979 founding and its 2014 acquisition by Schwabe Extracta (one of the world's largest herbal medicine manufacturers), the brand has maintained GMP-certified manufacturing, science-backed formulations, and a professional-channel distribution model that self-selects for clinicians who demand quality evidence for their patients.
How does Cortisol Manager work and is it effective?
How does Cortisol Manager work and is it effective?
Cortisol Manager combines Ashwagandha (Sensoril standardized extract), Phosphatidylserine, and L-Theanine to modulate the cortisol stress response and support sleep onset. Clinical evidence for Ashwagandha at standardized doses is solid (KSM-66 and Sensoril both have RCT support), and Phosphatidylserine has strong evidence for blunting exercise-induced cortisol. It's one of the brand's most clinically credentialed products.
What is SBI Protect and who should take it?
What is SBI Protect and who should take it?
SBI Protect delivers 500mg of serum-derived bovine immunoglobulins (secretory IgG) per serving — a unique ingredient that binds and neutralizes gut pathogens, supports gut-barrier integrity, and modulates intestinal immune activity. It's primarily used under practitioner guidance for leaky gut, IBS, inflammatory bowel concerns, and post-antibiotic gut restoration. It is not a standard probiotic — it works via immune-passthrough rather than bacterial colonization.
What is the difference between Integrative Therapeutics and typical store-brand supplements?
What is the difference between Integrative Therapeutics and typical store-brand supplements?
The key differences are formulation intent and channel. Integrative Therapeutics designs products to meet clinical scrutiny — licensed healthcare professionals will not recommend products that under-dose or use proprietary blends they can't justify to patients. This drives the brand to use clinically researched doses, disclose ingredient amounts, and maintain GMP manufacturing. Retail brands are optimized for shelf presence and price; Integrative Therapeutics is optimized for clinical defensibility.
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This content is for informational purposes only and does not constitute medical advice. Statements about dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary — consult your healthcare provider before starting any supplement. Full disclaimer























