SupplementScience

Best Vitamin D+K Supplements (2026)

DJP
Reviewed by , MD, Board Certified Internal Medicine

This content is for informational purposes only and does not constitute medical advice. Consult your healthcare provider before starting any supplement. Full disclaimer

Our Verdict

The best vitamin D+K supplement pairs D3 (cholecalciferol) at 2,000-5,000 IU with K2 as MK-7 (100-200mcg) for safe calcium metabolism and bone health.

Best By Category

#4Best for Overall / Best Value D3+K2:Sports Research Vitamin D3 + K2
#1Best for Maintenance Dose:Peak Performance Vitamin D+K 2000 IU
#6Best for Athletes / Flexible Dosing:Thorne D/K2 Liquid
#5Best for Budget D3+K2:Bronson Vitamin D3 + K2

TL;DR — Quick Answer

The best vitamin D+K supplement provides vitamin D3 (cholecalciferol) paired with vitamin K2 in the MK-7 form, which has a longer half-life than MK-4. For most adults, 2,000-5,000 IU of D3 with 100-200mcg of K2 daily is the optimal range. Always test your serum 25(OH)D levels to determine your ideal dose.

We evaluated 20 vitamin D+K combination supplements across D3 form, K2 (MK-7) content, IU dosing, third-party testing, and value. Pairing vitamin D3 with K2 ensures calcium goes to your bones, not your arteries.

Our recommendations are based on published research, not commission rates. Some links below are affiliate links — we may earn a commission at no extra cost to you. How we evaluate products

Quick Comparison

#1Peak Performance Vitamin D+K 2000 IU
9.1/10
Peak Performance
Best for: Daily maintenance dose with K2 for calcium metabolism
Vitamin D3 2000 IU + Vitamin K2 (MK-7) · 2,000 IU D3 + K2 (MK-7) per serving
Capsule · Third-Party Tested
~$0.25View on Amazon
#2Peak Performance Vitamin D+K 10,000 IU
8.9/10
Peak Performance
Best for: Deficiency correction under medical guidance
Vitamin D3 10,000 IU + Vitamin K2 (MK-7) · 10,000 IU D3 + K2 (MK-7) per serving
Capsule · Third-Party Tested
~$0.30View on Amazon
#3Peak Performance Vitamin D 5000 IU
8.7/10
Peak Performance
Best for: Mid-range dose without K2
Vitamin D3 5,000 IU · 5,000 IU D3 per serving
Capsule · Third-Party Tested
~$0.20View on Amazon
#4Sports Research Vitamin D3 + K2 (5000 IU)
9.4/10
Sports Research
Best for: Best overall D3+K2 combination
Vitamin D3 (5,000 IU) + K2 (MK-7, 100mcg) in Coconut Oil · 5,000 IU D3 + 100mcg K2 per softgel
Softgel with coconut oil · USP Verified
~$0.13View on Amazon
#5Bronson Vitamin D3 + K2 (5000 IU)
8.7/10
Bronson
Best for: Best budget D3+K2 combination
Vitamin D3 (5,000 IU) + K2 (MK-7, 90mcg) · 5,000 IU D3 + 90mcg K2 per capsule
Vegetarian capsule · GMP Certified, Third-Party Tested
~$0.06View on Amazon
#6Thorne D/K2 Liquid
9/10
Thorne
Best for: Athletes and precise dose adjustment
Vitamin D3 (1,000 IU) + K2 (200mcg) per drop in MCT Oil · 1,000 IU D3 + 200mcg K2 per drop (adjustable)
Liquid drops in MCT oil · NSF Certified for Sport
~$0.23View on Amazon

Detailed Reviews

Top Pick
1

Peak Performance Vitamin D+K 2000 IU

Peak Performance

9.1/10
~$0.25/serving
Ingredient: Vitamin D3 2000 IU + Vitamin K2 (MK-7)
Dose: 2,000 IU D3 + K2 (MK-7) per serving
Form: Capsule
Testing: Third-Party Tested
2,000 IU D3 + K2 (MK-7) per servingClinical range: 1,000-5,000 IU D3 + 100-200mcg K2
Clinical dose

Why we recommend it: Ideal maintenance dose of 2,000 IU D3 paired with K2 (MK-7) for proper calcium utilization. Third-party tested for purity. The D3+K2 combination helps direct calcium to bones and teeth rather than soft tissues and arteries.

Best for: Daily maintenance dose with K2 for calcium metabolism

Pros

  • Ideal maintenance dose (2,000 IU)
  • Includes K2 (MK-7)
  • Third-party tested
  • Good value ($0.25/serving)

Cons

  • May be insufficient for deficiency
  • No fat carrier for absorption
  • Capsule form only
Gluten-freeNon-GMO
Check Price on Amazon(paid link)
2

Peak Performance Vitamin D+K 10,000 IU

Peak Performance

8.9/10
~$0.30/serving
Ingredient: Vitamin D3 10,000 IU + Vitamin K2 (MK-7)
Dose: 10,000 IU D3 + K2 (MK-7) per serving
Form: Capsule
Testing: Third-Party Tested
10,000 IU D3 + K2 (MK-7) per servingClinical range: 1,000-5,000 IU D3 + 100-200mcg K2
Therapeutic dose

Why we recommend it: High-potency 10,000 IU dose for rapid deficiency correction. Paired with K2 (MK-7) to ensure safe calcium metabolism at higher D3 doses. Third-party tested for purity and potency.

Best for: Deficiency correction under medical guidance

Pros

  • Rapid deficiency correction
  • Includes K2 for high-dose safety
  • Third-party tested
  • Good value for high-dose ($0.30/serving)

Cons

  • Requires medical supervision
  • Not for daily maintenance
  • Risk of hypercalcemia if unsupervised
Gluten-freeNon-GMO
Check Price on Amazon(paid link)
3

Peak Performance Vitamin D 5000 IU

Peak Performance

8.7/10
~$0.20/serving
Ingredient: Vitamin D3 5,000 IU
Dose: 5,000 IU D3 per serving
Form: Capsule
Testing: Third-Party Tested
5,000 IU D3 per servingClinical range: 1,000-5,000 IU D3
Clinical dose

Why we recommend it: Popular 5,000 IU dosage for those who need more than maintenance but less than deficiency-correction levels. Clean formula with third-party testing. Good option if you already get K2 from diet or another supplement.

Best for: Mid-range dose without K2

Pros

  • Popular 5,000 IU dose
  • Clean single-ingredient formula
  • Third-party tested
  • Most affordable option ($0.20/serving)

Cons

  • No K2 included
  • May need separate K2 supplement
  • No fat carrier for absorption
Gluten-freeNon-GMO
Check Price on Amazon(paid link)
4

Sports Research Vitamin D3 + K2 (5000 IU)

Sports Research

9.4/10
~$0.13/serving
Ingredient: Vitamin D3 (5,000 IU) + K2 (MK-7, 100mcg) in Coconut Oil
Dose: 5,000 IU D3 + 100mcg K2 per softgel
Form: Softgel with coconut oil
Testing: USP Verified
5,000 IU D3 + 100mcg K2 per softgelClinical range: 1,000-5,000 IU D3 + 100-200mcg K2
Clinical dose

Why we recommend it: The gold standard D3+K2 supplement. USP Verified for guaranteed potency. Coconut oil carrier enhances absorption of these fat-soluble vitamins. Combines 5,000 IU D3 with 100mcg K2 (MK-7) in a single softgel at an exceptional $0.13/serving. Over 50,000 Amazon reviews with a 4.8-star average.

Best for: Best overall D3+K2 combination

Pros

  • USP Verified (gold standard testing)
  • Coconut oil for absorption
  • D3+K2 in one softgel
  • Exceptional value ($0.13/serving)

Cons

  • 5,000 IU may exceed some needs
  • K2 dose on lower end (100mcg)
  • Should test levels before starting
Gluten-freeNon-GMOSoy-free
Check Price on Amazon(paid link)
5

Bronson Vitamin D3 + K2 (5000 IU)

Bronson

8.7/10
~$0.06/serving
Ingredient: Vitamin D3 (5,000 IU) + K2 (MK-7, 90mcg)
Dose: 5,000 IU D3 + 90mcg K2 per capsule
Form: Vegetarian capsule
Testing: GMP Certified, Third-Party Tested
5,000 IU D3 + 90mcg K2 per capsuleClinical range: 1,000-5,000 IU D3 + 100-200mcg K2
Clinical dose

Why we recommend it: Incredible value at approximately $0.06/serving for a D3+K2 combination — the cheapest per-serving option by a wide margin. Bronson has been manufacturing supplements since 1960 with GMP certification. 250-count bottle provides over 8 months of daily supplementation.

Best for: Best budget D3+K2 combination

Pros

  • Best value ($0.06/serving)
  • 60+ year supplement brand
  • 250-count bottle (8+ months)
  • D3+K2 combination

Cons

  • No USP or NSF verification
  • 90mcg K2 (below ideal range)
  • No fat carrier in capsule
  • Less well-known brand
VegetarianGluten-freeNon-GMO
Check Price on Amazon(paid link)
6

Thorne D/K2 Liquid

Thorne

9/10
~$0.23/serving
Ingredient: Vitamin D3 (1,000 IU) + K2 (200mcg) per drop in MCT Oil
Dose: 1,000 IU D3 + 200mcg K2 per drop (adjustable)
Form: Liquid drops in MCT oil
Testing: NSF Certified for Sport
1,000 IU D3 + 200mcg K2 per drop (adjustable)Clinical range: 1,000-5,000 IU D3 + 100-200mcg K2
Clinical dose

Why we recommend it: NSF Certified for Sport makes this ideal for drug-tested athletes. Liquid drops allow precise dose adjustment — take 1 drop for maintenance (1,000 IU) or 5 drops for deficiency correction (5,000 IU). MCT oil carrier maximizes absorption. 200mcg K2 per drop is the highest K2 dose on our list. Thorne is trusted by professional sports teams.

Best for: Athletes and precise dose adjustment

Pros

  • NSF Certified for Sport
  • Fully adjustable dosing
  • MCT oil for absorption
  • Highest K2 dose (200mcg/drop)

Cons

  • Premium price ($0.23/serving)
  • Requires refrigeration
  • Must count drops
  • Glass bottle less portable
Gluten-freeSoy-freeDairy-free
Check Price on Amazon(paid link)

How to Choose

Vitamin D3 (cholecalciferol) is significantly more effective than D2 (ergocalciferol) at raising and maintaining serum 25(OH)D levels. When taking D3, pairing with vitamin K2 in the MK-7 form is important — K2 activates proteins that direct calcium to bones and teeth while keeping it out of arteries and soft tissues. The MK-7 form of K2 has a half-life of about 72 hours (vs 4-6 hours for MK-4), providing more consistent levels. Start with 2,000 IU daily for maintenance, get blood work done after 8-12 weeks, and adjust from there. Take with your fattiest meal for optimal absorption.

How We Evaluate

Every product is scored against these weighted criteria. Our ratings reflect clinical evidence and product quality, not commission rates.

K2 (MK-7) Inclusion

30%

Vitamin K2 in the MK-7 form (72-hour half-life) is essential at D3 doses above 2,000 IU. Products without K2 score lower for calcium safety.

Third-Party Testing

25%

USP, NSF, or independent testing ensures accurate potency of fat-soluble vitamins, which are commonly over- or under-dosed.

D3 Dose Flexibility

20%

Optimal D3 dose varies by individual (1,000-5,000 IU). Products with adjustable serving sizes (liquids) or multiple IU options score higher.

Absorption Enhancement

15%

Fat-soluble vitamins require dietary fat for absorption. Products with built-in fat carriers (MCT oil, coconut oil, olive oil) improve bioavailability.

Value

10%

Cost per serving adjusted for D3 dose and K2 inclusion. A D3+K2 combo at $0.13/serving beats separate purchases.

Frequently Asked Questions

Why should I take vitamin K2 with vitamin D3?

Vitamin D3 increases calcium absorption from food, but without K2, that calcium may deposit in arteries and soft tissues rather than bones. Vitamin K2 activates osteocalcin (which pulls calcium into bones) and matrix GLA protein (which prevents arterial calcification). This is especially important at higher D3 doses above 2,000 IU daily.

What is the difference between vitamin K2 MK-4 and MK-7?

MK-4 and MK-7 are both forms of vitamin K2, but MK-7 has a much longer half-life (about 72 hours vs 4-6 hours for MK-4). This means MK-7 maintains more consistent blood levels with once-daily dosing. MK-7 is also effective at lower doses (100-200mcg vs 15-45mg for MK-4). Most D3+K2 supplements use MK-7 for these reasons.

How much vitamin K2 should I take with vitamin D3?

Most experts recommend 100-200mcg of K2 (MK-7) per day when taking 2,000-5,000 IU of D3. At higher D3 doses (10,000 IU), some practitioners suggest 200-300mcg of K2. There is no established tolerable upper limit for K2 — it has not shown toxicity even at high doses in clinical studies. The important thing is to include some K2 rather than debating the exact amount.

Can I take vitamin D+K if I am on blood thinners?

Vitamin K2 can interfere with warfarin (Coumadin) and other vitamin K antagonist blood thinners by counteracting their mechanism. If you are on warfarin, do NOT take K2 without your doctor's approval and INR monitoring. Direct oral anticoagulants (DOACs) like apixaban and rivarelbatan work differently and are generally not affected by K2, but still consult your doctor.

What foods contain vitamin K2?

The richest dietary source of K2 (MK-7) is natto (Japanese fermented soybeans) — a single serving provides ~1,000mcg. Other sources include gouda cheese (~75mcg per 100g), egg yolks (~32mcg per yolk), chicken liver, and grass-fed butter. Most Western diets provide only 10-30mcg of K2 daily, well below the 100-200mcg recommended for optimal bone and cardiovascular health.

Should I take D3+K2 in the morning or at night?

Take D3+K2 with your largest or fattiest meal of the day, regardless of time. Both are fat-soluble and absorption increases up to 50% with dietary fat. Some people find high-dose vitamin D mildly energizing and prefer morning dosing, but there is no clinical evidence that timing matters. Consistency with a fat-containing meal is what matters most.

How long does it take for vitamin D supplements to raise blood levels?

At 2,000 IU daily, most people see meaningful increases in serum 25(OH)D within 4-6 weeks, with full steady-state levels reached at 8-12 weeks. Higher doses (5,000 IU) raise levels faster but should be monitored with blood work. Get tested before starting and retest after 8-12 weeks to determine if your dose needs adjustment.

References

  1. (). Vitamin D toxicity redefined: vitamin K and the molecular mechanism. Medical Hypotheses. DOI
  2. (). Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women. Osteoporosis International. DOI
  3. (). The Synergistic Interplay between Vitamins D and K for Bone and Cardiovascular Health. International Journal of Endocrinology. DOI
  4. (). Vitamin K-containing dietary supplements: comparison of synthetic vitamin K1 and natto-derived menaquinone-7. Blood. DOI